86134-80-7

Basic information

• Product Name: 3-amino-4-({3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino)cyclobut-3-ene-1,2-dione
• Synonyms: 3-Cyclobutene-1,2-dione, 3-amino-4-((3-(3-(1-piperidinylmethyl)phenoxy)propyl)amino)-
• CAS NO: 86134-80-7
• Molecular Formula: C₁₉H₂₅N₃O₃
• Molecular Weight: 343.4201
• Mol File: 86134-80-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 501.4°C at 760 mmHg
• Flash Point: 257.1°C
• Density: 1.24g/cm³
• Vapor Pressure: 3.48E-10mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: 3-amino-4-({3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino)cyclobut-3-ene-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-4-({3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino)cyclobut-3-ene-1,2-dione(86134-80-7)
• EPA Substance Registry System: 3-amino-4-({3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino)cyclobut-3-ene-1,2-dione(86134-80-7)

Safety Data

• Hazardous Substances Data: 86134-80-7(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 120096-84-6 1-amino-2-[3-(3-formylphenoxy)propylamino]-1-cyclobutene-3,4-dione 
• 100-83-4 meta-hydroxybenzaldehyde 
• 120370-37-8 1-butoxy-2-[3-(3-piperidinomethylphenoxy)propylamino]-1-cyclobutene-3,4-dione 
• 120356-93-6 1-butoxy-2-(3-bromopropylamino)-1-cyclobutene-3,4-dione 
• 73279-04-6 3-[1-piperidinylmethyl]phenol 
• 73278-98-5 N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>amine 
• 5231-88-9 1-Amino-2-methoxy-cyclobut-1-ene-3,4-dione 
• 5222-73-1 3,4-dimethoxy-3-cyclobutene-1,2-dione 
• 1336-21-6 ammonium hydroxide 

Relevant articles and documents

SUBSTITUTED 3-CYCLOBUTENE-1,2-DIONE INTERMEDIATES

The present invention relates to novel intermediates of the formula STR1 wherein R is lower alkyl or cyclohexyl, and X is hydroxy or a conventional leaving group, and the use thereof in a process for the preparation of certain histamine H 2-antagonists.

CHEMICAL COMPOUNDS

Compounds of the formula STR1 wherein R 12 is a leaving group, Z is S, O or CH 2 and A is a phenyl, furyl, thienyl or pyridyl ring substituted by a STR2 moiety, in which R 8 and R 9 are various substituents or, when taken together with the nitrogen, may be a specified heterocyclic ring, are intermediates in the preparation of histamine H 2-antagonist anti-ulcer agents of the formula STR3 in which R 1 and R 2 are any of several specified substituents.