863513-91-1 Usage
Description
GRT6005 is a high-quality, pure glycerol product derived from renewable resources. It is a colorless, odorless, and viscous liquid with a sweet taste. Glycerol is a versatile and essential chemical compound with a wide range of applications across various industries due to its unique properties, such as its hygroscopic nature, solubility in water, and ability to act as a humectant, solvent, and emulsifier.
Uses
Used in the Pharmaceutical Industry:
GRT6005 is used as a pharmaceutical excipient for its humectant properties, which helps maintain the moisture content in medications and ensures their stability and effectiveness. It is also used as a solvent for various active pharmaceutical ingredients (APIs) and in the production of suppositories, elixirs, and liquid medications.
Used in the Food and Beverage Industry:
Glycerol is used as a humectant to retain moisture in food products, preventing them from drying out and extending their shelf life. It is also used as a sweetener and flavor enhancer in various food and beverage products, such as candies, baked goods, and soft drinks.
Used in the Cosmetics and Personal Care Industry:
Glycerol is used as a humectant in cosmetics and personal care products, such as lotions, creams, and shampoos, to help retain moisture and improve skin hydration. It also acts as an emulsifier, helping to blend oil and water-based ingredients, and as a solvent for various cosmetic ingredients.
Used in the Agriculture Industry:
Glycerol is used in the agriculture industry as a foliar spray to improve plant growth and health. It helps in the absorption of nutrients and water, leading to increased crop yields and better resistance to environmental stress.
Used in the Chemical Industry:
GRT6005 is used as a raw material in the production of various chemicals, such as nitroglycerin, which is used in the manufacture of explosives, and as a building block in the synthesis of other complex organic compounds.
Used in the Energy Industry:
Glycerol can be used as a feedstock for the production of biofuels, such as biodiesel and bioethanol, contributing to the development of sustainable and renewable energy sources.
Used in the Textile Industry:
Glycerol is used in the textile industry as a humectant and lubricant in the manufacturing process, improving the softness, flexibility, and durability of fabrics.
Used in the Paper and Pulp Industry:
Glycerol is used in the paper and pulp industry as a plasticizer to improve the flexibility and strength of paper products, as well as a retention aid to enhance the retention of fillers and fibers during the papermaking process.
Used in the Automotive Industry:
Glycerol is used in the automotive industry as a component in antifreeze and coolant formulations, helping to prevent freezing and corrosion in engine cooling systems.
Used in the Fine Chemicals Industry:
GRT6005 is used as a starting material or intermediate in the synthesis of various fine chemicals, such as tritium-labeled probes for autoradiography studies, which are used in research and diagnostic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 863513-91-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,3,5,1 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 863513-91:
(8*8)+(7*6)+(6*3)+(5*5)+(4*1)+(3*3)+(2*9)+(1*1)=181
181 % 10 = 1
So 863513-91-1 is a valid CAS Registry Number.
863513-91-1Relevant articles and documents
Improved and Flexible Synthetic Access to the Spiroindole Backbone of Cebranopadol
Christoffers, Jens,Schmidtmann, Marc,Wachtendorf, Daniel
supporting information, p. 6420 - 6423 (2020/09/02)
By changing the dimethylamino to a nitro group, a novel synthetic access to the spirocyclic opioid analgesic cebranopadol was developed that is much more efficient compared with the established route. On the basis of the α-acidity of α-nitrotoluene, the two-fold Michael addition to acrylate gave an acyclic precursor compound, which was easily transformed by Dieckmann condensation and decarboxylation to the cyclohexanone derivative needed for the annulation of the indole ring by an oxa-Pictet-Spengler reaction. As an additional benefit, the reduction of the nitro group furnished an amine, which could be late-stage-diversified to carboxamides, sulfonamides, ureas, and N-alkyl congeners. The transformation of the nitro group at the spirocyclic scaffold to the dimethylamino function of the actual title compound was achieved in one step with zinc/formic acid/formaldehyde in 83% yield.
CRYSTALLINE (1R,4R)-6'-FLUORO-N,N-DIMETHYL-4-PHENYL-4',9'-DIHYDRO-3'H-SPIRO[CYCLOHEXANE-1,1'-PYRANO[3,4,B]INDOL]-4-AMINE
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Paragraph 0410, (2013/03/26)
Crystalline forms of (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine, pharmaceutical compositions and medicaments comprising these crystalline modifications, the use of these modifications as well as a process for the enrichment of such crystalline modifications.
Process for the preparation of (1r,4r)-6'-fluoro-(N,N-dimethyl- and N-methyl)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine
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Paragraph 0126, (2013/06/27)
A process for the preparation of (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4b]indol]-4-amine and (1r,4r)-6′-fluoro-N-methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4b]-indol]-4-amine or physiologically acceptable acid addition salts thereof.
