864224-08-8 Usage
Description
2-(Phenylethynyl)-7,8-dihydroquinolin-5(6H)-one is a quinolone derivative, a heterocyclic compound characterized by a quinoline ring system with a phenyl group attached to the carbon atom at position two. This structural feature endows it with potential pharmacological applications, making it a promising candidate for drug development or as a building block in the synthesis of other bioactive compounds.
Uses
Used in Pharmaceutical Industry:
2-(Phenylethynyl)-7,8-dihydroquinolin-5(6H)-one is used as a drug candidate for its potential pharmacological properties. Its specific application may vary depending on the context and the therapeutic target it is designed to address.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-(Phenylethynyl)-7,8-dihydroquinolin-5(6H)-one serves as a building block for the creation of other bioactive compounds. Its unique structure allows for the development of new molecules with potential applications in various therapeutic areas.
Check Digit Verification of cas no
The CAS Registry Mumber 864224-08-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,4,2,2 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 864224-08:
(8*8)+(7*6)+(6*4)+(5*2)+(4*2)+(3*4)+(2*0)+(1*8)=168
168 % 10 = 8
So 864224-08-8 is a valid CAS Registry Number.
864224-08-8Relevant articles and documents
Positive and negative modulation of group I metabotropic glutamate receptors
Vanejevs, Maksims,Jatzke, Claudia,Renner, Steffen,Müller, Sibylle,Hechenberger, Mirko,Bauer, Tanja,Klochkova, Anna,Pyatkin, Ilya,Kazyulkin, Denis,Aksenova, Elena,Shulepin, Sergey,Timonina, Olga,Haasis, Ariane,Gutcaits, Aleksandrs,Parsons, Christopher G.,Kauss, Valerjans,Weil, Tanja
, p. 634 - 647 (2008/09/19)
A discriminating pharmacophore model for noncompetitive metabotropic glutamate receptor antagonists of subtype 1 (mGluR1) was developed that facilitated the discovery of moderately active mGluR1 antagonists. One scaffold was selected for the design of sev
TETRAHYDROQUINOLINONES AND THEIR USE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS
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Page/Page column 30, (2008/06/13)
The invention relates to ethynyl-substituted tetrahydroquinolinone derivatives as well as their pharmaceutically acceptable a salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are group
Tetrahydroquinolinones and their use as antagonists of metabotropic glutamate receptors
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Page/Page column 36, (2008/06/13)
The invention relates to tetrahydroquinolinone derivatives as well as their pharmaceutially acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are group I mGluR antagonists an
