872782-53-1

Basic information

• Product Name: 2-(4-methoxyphenyl)-N-phenylpropanamide
• Synonyms: 2-(4-methoxyphenyl)-N-phenylpropanamide
• CAS NO: 872782-53-1
• Molecular Weight: 255.316
• Mol File: 872782-53-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)-N-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-N-phenylpropanamide(872782-53-1)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-N-phenylpropanamide(872782-53-1)

Safety Data

• Hazardous Substances Data: 872782-53-1(Hazardous Substances Data)

Upstream product

• 637-69-4 4-Methoxystyrene 
• 201230-82-2 carbon monoxide 
• 62-53-3 aniline 
• 95111-00-5 1-(1,1-dibromoprop-1-en-2-yl)-4-methoxylbenzene 

Relevant articles and documents

Asymmetric Markovnikov Hydroaminocarbonylation of Alkenes Enabled by Palladium-Monodentate Phosphoramidite Catalysis

A palladium-catalyzed asymmetric Markovnikov hydroaminocarbonylation of alkenes with anilines has been developed for the atom-economical synthesis of 2-substituted propanamides bearing an α-stereocenter. A novel phosphoramidite ligand L16 was discovered which exhibited very high reactivity and selectivity in the reaction. This asymmetric Markovnikov hydroaminocarbonylation employs readily available starting materials and tolerates a wide range of functional groups, thus providing a facile and straightforward method for the regio- and enantioselective synthesis of 2-substituted propanamides under ambient conditions. Mechanistic studies revealed that the reaction proceeds through a palladium hydride pathway.