873387-14-5Relevant articles and documents
Highly efficient carbazolyl-derived phosphine ligands: Application to sterically hindered biaryl couplings
Chun To, Sheung,Yee Kwong, Fuk
supporting information; experimental part, p. 5079 - 5081 (2011/06/10)
A new family of phosphine ligands bearing a bulky carbazolyl scaffold is described. With the combination of ligand 2a and Pd(OAc)2, difficult tri-ortho-substituted biaryl couplings are accomplished smoothly. In particular, the catalyst loading as low as 0.02 mol% of Pd for non-activated 2,6-disubstituted aryl chloride coupling can be achieved.