877264-74-9 Usage
Molecular Weight
294.14 g/mol
Structure
1H-Indazole-1-carboxylic acid, 5-(2-bromoacetyl)-, 1,1-dimethylethyl ester is an indazole derivative with a bromoacetyl group at the 5-position and a dimethylethyl ester group at the 1-position.
+ Appearance
Pale yellow solid
+ Melting Point
Not provided in the material
+ Solubility
Not provided in the material
+ Reactivity
1H-Indazole-1-carboxylic acid, 5-(2-bromoacetyl)-, 1,1-dimethylethyl ester may undergo reactions that are typical for indazole derivatives, such as electrophilic substitution and nucleophilic substitution.
+ Stability
Stable under normal conditions, but may decompose upon exposure to heat or light.
+ Therapeutic Potential
1H-Indazole-1-carboxylic acid, 5-(2-bromoacetyl)-, 1,1-dimethylethyl ester has shown potential therapeutic properties in the treatment of various diseases and disorders.
+ Biological Assays
The compound has shown promising results in biological assays, making it a valuable compound for further study and potential application in the medical field.
+ Class
1H-Indazole-1-carboxylic acid, 5-(2-bromoacetyl)-, 1,1-dimethylethyl ester belongs to the class of indazole derivatives.
+ Usage
It is commonly used in pharmaceutical research and drug development as an important component in the synthesis of new drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 877264-74-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,7,2,6 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 877264-74:
(8*8)+(7*7)+(6*7)+(5*2)+(4*6)+(3*4)+(2*7)+(1*4)=219
219 % 10 = 9
So 877264-74-9 is a valid CAS Registry Number.
877264-74-9Relevant articles and documents
5-HETEROARYL SUBSTITUTED INDAZOLES AS KINASE INHIBITORS
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, (2009/01/24)
The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, R1, R2, R3 and m, are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.
