88498-93-5Relevant articles and documents
Synthesis of New 2-Substituted Benzylidenethiazolobenzimidazol-3(2H)-ones and Their Biological Activity
Soni, Namita,Barthwal, J. P.,Gupta, T. K.,Bhalla, T. N.,Parmar, S. S.,Bhargava, K. P.
, p. 785 - 788 (2007/10/02)
2-Substituted benzylidenethiazolobenzimidazol-3(2H)-ones (I-XIV) have been synthesized and found to possess anticonvulsant activity (0-60percent).These compounds also inhibit rat brain monoamine oxidase (MAO) (33.70-98.30percent) and succinate dehydrogenase (SDH) (25.72-78.95percent) in vitro of concentrations 4E-4 M and 6E-4 M, respectively.Structure-activity relationship has been dicussed.