888715-86-4

Basic information

• Product Name: (R)-4-methyl-N-(2-oxo-piperidin-3-yl)-benzenesulfonamide
• Synonyms: (R)-4-methyl-N-(2-oxo-piperidin-3-yl)-benzenesulfonamide
• CAS NO: 888715-86-4
• Molecular Weight: 268.337
• Mol File: 888715-86-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-methyl-N-(2-oxo-piperidin-3-yl)-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-methyl-N-(2-oxo-piperidin-3-yl)-benzenesulfonamide(888715-86-4)
• EPA Substance Registry System: (R)-4-methyl-N-(2-oxo-piperidin-3-yl)-benzenesulfonamide(888715-86-4)

Safety Data

• Hazardous Substances Data: 888715-86-4(Hazardous Substances Data)

Upstream product

• 16682-12-5 D-ornithine hydrochloride 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Highly efficient, enantioselective syntheses of (S)-(+)- and (R)-(-)-dapoxetine starting with 3-phenyl-1-propanol

(Chemical Equation Presented) A highly efficient, enantioselective sequence has been developed for the synthesis of (S)- and (R)-dapoxetine. The pathways involve the intermediacy of the 6-membered-ring sulfamate esters 4, which were generated by Du Bois asymmetric C-Hamination reactions of the prochiral sulfamate 3, catalyzed by the chiral dirhodium(II) complexes. During the course of our research, the absolute configuration of the enantiomer of 4-pheny[1,2,3]oxathiazinane 2,2-dioxide (4r), prepared by the Du Bois asymmetric C-H amination reaction of 3 and the Rh2(S-nap)4 catalyst, is determined to be R and not S as was originally reported.