89459-38-1

Basic information

• Product Name: 2-Iodo-4-nitrobenzoic acid
• Synonyms: 2-Iodo-4-nitrobenzoic acid
• CAS NO: 89459-38-1
• Molecular Formula: C₇H₄INO₄
• Molecular Weight: 293.01543
• EINECS: 604-604-1
• Mol File: 89459-38-1.mol
• Article Data: 23

Chemical Properties

• Melting Point: 142 °C
• Boiling Point: 402.8±35.0 °C(Predicted)
• Appearance: /
• Density: 2.156±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 1.99±0.13(Predicted)
• CAS DataBase Reference: 2-Iodo-4-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Iodo-4-nitrobenzoic acid(89459-38-1)
• EPA Substance Registry System: 2-Iodo-4-nitrobenzoic acid(89459-38-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 89459-38-1(Hazardous Substances Data)

Usage

General Description

2-Iodo-4-nitrobenzoic acid is a chemical compound with the molecular formula C7H4INO4. It is an aromatic compound that contains both a nitro group and an iodo group attached to a benzene ring. 2-Iodo-4-nitrobenzoic acid is commonly used as a building block in the synthesis of various pharmaceutical and organic compounds due to its ability to participate in a variety of organic reactions. It is also used as a reagent in the preparation of other complex chemical compounds. 2-Iodo-4-nitrobenzoic acid is a yellow crystalline solid that is slightly soluble in water and soluble in organic solvents, making it versatile and easily manipulable in a laboratory setting.

Upstream product

• 64-17-5 ethanol 
• 112391-34-1 4-nitro-2-iodosobenzoic acid 
• 62-23-7 4-nitro-benzoic acid 
• 619-17-0 4-Nitroanthranilic acid 
• 108-24-7 acetic anhydride 
• 7745-92-8 2-iodo-1-methyl-4-nitrobenzene 

Downstream Products

• 6326-42-7 2-iodo-4-nitrobenzoic acid methyl ester 
• 112391-35-2 4-nitro-2-iodoxybenzoic acid 
• 89459-39-2 5-Nitrodiphenyliodonium-2-carboxylate 
• 73655-51-3 4-amino-2-iodobenzoic acid 
• 116631-87-9 4-hydroxy-2-iodo-benzoic acid 

Relevant articles and documents

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Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome

A novel series of guanidinebenzoate enteropeptidase and trypsin dual inhibitors has been discovered and SAR studies were conducted. Optimization was focused on improving properties for gut restriction, including increased aqueous solubility, lower cellular permeability, and reduced oral bioavailability. Lead compounds were identified with efficacy in a mouse fecal protein excretion study.

PARA-AMINO-BENZYL LINKERS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN CONJUGATES

The present invention relates to para-amino-benzyl linker compounds useful for linking drug moieties to antibodies, to linker-drug compounds in which said para-amino-benzyl linker compounds are covalently linked to drug moieties, and to antibody-drug conjugates in which said para-amino-benzyl linker compounds are covalently linked to drug wherein said drug is enzymatically cleaved from the conjugate at a particular cell or tissue type targeted by said antibody.