89487-91-2

Basic information

• Product Name: 2-IODO-4-NITROPHENOL
• Synonyms: 2-IODO-4-NITROPHENOL;IFLAB-BB F0243-0017;4-Hydroxy-3-iodonitrobenzene;Phenol, 2-iodo-4-nitro-;2-Iodo-4-nitrophenol 97%;2-Iodo-4-nitrophenol97%
• CAS NO: 89487-91-2
• Molecular Formula: C₆H₄INO₃
• Molecular Weight: 265.01
• Product Categories: Aromatic Phenols
• Mol File: 89487-91-2.mol
• Article Data: 37

Chemical Properties

• Melting Point: 89-94°C
• Boiling Point: 294.5 °C at 760 mmHg
• Flash Point: 131.9 °C
• Appearance: /
• Density: 2.176 g/cm³
• Vapor Pressure: 0.000919mmHg at 25°C
• Refractive Index: 1.71
• Storage Temp.: 2-8°C
• BRN: 2519781
• CAS DataBase Reference: 2-IODO-4-NITROPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODO-4-NITROPHENOL(89487-91-2)
• EPA Substance Registry System: 2-IODO-4-NITROPHENOL(89487-91-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 89487-91-2(Hazardous Substances Data)

Usage

Uses

2-Iodo-4-nitrophenol is used as a reactant in the preparation of iodophenols.

InChI:InChI=1/C6H4INO3/c7-5-3-4(8(10)11)1-2-6(5)9/h1-3,9H

Upstream product

• 100-02-7 4-nitro-phenol 
• 533-58-4 2-Iodophenol 
• 81681-49-4 2-iodo-4-nitroso-phenol 
• 7553-56-2 iodine 
• 7782-68-5 iodic acid 
• 609-73-4 o-nitroiodobenzene 
• 72212-81-8 2-hydroxy-5-nitrodiphenyliodonium ylide 
• 5399-03-1 2-iodo-1-methoxy-4-nitrobenzene 
• 139-02-6 sodium phenoxide 
• 615-43-0 2-iodophenylamine 
• 108-95-2 phenol 
• 540-38-5 p-Iodophenol 
• 99-57-0 2-hydroxy-5-nitroaniline 
• 7697-37-2 nitric acid 

Downstream Products

• 714964-32-6 (2S,3R,4R)-4-(4-Azido-2-iodo-phenoxy)-3-methoxycarbonylmethyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 100875-11-4 (2-iodo-4-nitro-phenyl)-octyl ether 
• 1007383-08-5 2-[N-allyl-N-(2-iodo-4-nitrophenyl)amino]-N-(4-chlorobenzyl)-4-methylpentanamide 
• 1393596-21-8 C₂₉H₂₈IN₃O₈ 
• 89640-51-7 4-amino-2-iodophenol 
• 16237-97-1 5-nitro-2-phenylbenzofuran 
• 141644-94-2 N-(2-butyl-3-{[4-(3-dibutylaminopropoxy)-phenyl]-hydroxymethyl}-benzofuran-5-yl)-methanesulfonamide 
• 76263-55-3 2-Iodo-4-nitro-1-(4-nitro-phenoxy)-benzene 

Relevant articles and documents

Visible-Light-Induced Radical Carbo-Cyclization/ gem-Diborylation through Triplet Energy Transfer between a Gold Catalyst and Aryl Iodides

Geminal diboronates have attracted significant attention because of their unique structures and reactivity. However, benzofuran-, indole-, and benzothiophene-based benzylic gem-diboronates, building blocks for biologically relevant compounds, are unknown. A promising protocol using visible light and aryl iodides for constructing valuable building blocks, including benzofuran-, indole-, and benzothiophene-based benzylic gem-diboronates, via radical carbo-cyclization/gem-diborylation of alkynes with a high functional group tolerance is presented. The utility of these gem-diboronates has been demonstrated by a 10 g scale conversion, by versatile transformations, by including the synthesis of approved drug scaffolds and two approved drugs, and even by polymer synthesis. The mechanistic investigation indicates that the merging of the dinuclear gold catalyst (photoexcitation by 315-400 nm UVA light) with Na2CO3 is directly responsible for photosensitization of aryl iodides (photoexcitation by 254 nm UV light) with blue LED light (410-490 nm, λmax = 465 nm) through an energy transfer (EnT) process, followed by homolytic cleavage of the C-I bond in the aryl iodide substrates.

What Is the Structure of the Antitubercular Natural Product Eucapsitrione?

1,5,7-Trihydroxy-6H-indeno[1,2-b]anthracene-6,11,13-trione (1), proposed to be the antitubercular natural product eucapsitrione, has been synthesized in 43% overall yield and six steps, including a key Suzuki-Miyaura biaryl coupling and a directed remote

Cyclopropenones for Metabolic Targeting and Sequential Bioorthogonal Labeling

Cyclopropenones are attractive motifs for bioorthogonal chemistry, owing to their small size and unique modes of reactivity. Unfortunately, the fastest-reacting cyclopropenones are insufficiently stable for routine intracellular use. Here we report cyclop