900174-36-9Relevant articles and documents
Design and synthesis of phenylpyrrolidine phenylglycinamides as highly potent and selective TF-FVIIa inhibitors
Zhang, Xiaojun,Jiang, Wen,Jacutin-Porte, Swanee,Glunz, Peter W.,Zou, Yan,Cheng, Xuhong,Nirschl, Alexandra H.,Wurtz, Nicholas R.,Luettgen, Joseph M.,Rendina, Alan R.,Luo, Gang,Harper, Timothy M.,Wei, Anzhi,Anumula, Rushith,Cheney, Daniel L.,Knabb, Robert M.,Wong, Pancras C.,Wexler, Ruth R.,Priestley, E. Scott
supporting information, p. 188 - 192 (2014/03/21)
Inhibitors of the Tissue Factor/Factor VIIa (TF-FVIIa) complex are promising novel anticoagulants that show excellent efficacy and minimal bleeding in preclinical models. On the basis of a zwitterionic phenylglycine acylsulfonamide 1, a phenylglycine benz
BENZAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS
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Page/Page column 48, (2010/09/17)
The present invention provides novel benzamide derivatives of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, W, Y, Z, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
Sulfur chelated ruthenium compounds useful as olefin metathesis catalysts
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, (2009/07/03)
Sulfur chelated ruthenium compounds and methods and compositions involving the same. A method may relate to subjecting an olefin to a metathesis reaction in the presence of a sulfur chelated ruthenium compound. A composition may relate to an olefin starting material dissolved in an organic solvent together with a sulfur chelated ruthenium compound.