900174-37-0

Basic information

• Product Name: (E)-methyl 4-(2-(isopropylthio)-5-nitrobenzylideneamino)butanoate
• Synonyms: (E)-methyl 4-(2-(isopropylthio)-5-nitrobenzylideneamino)butanoate
• CAS NO: 900174-37-0
• Molecular Weight: 324.401
• Mol File: 900174-37-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (E)-methyl 4-(2-(isopropylthio)-5-nitrobenzylideneamino)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-methyl 4-(2-(isopropylthio)-5-nitrobenzylideneamino)butanoate(900174-37-0)
• EPA Substance Registry System: (E)-methyl 4-(2-(isopropylthio)-5-nitrobenzylideneamino)butanoate(900174-37-0)

Safety Data

• Hazardous Substances Data: 900174-37-0(Hazardous Substances Data)

Upstream product

• 900174-36-9 2-(isopropylthio)-5-nitrobenzaldehyde 
• 3251-07-8 methyl 4-aminobutyrate 
• 27996-87-8 2-fluoro-5-nitrobenzaldehye 
• 13031-60-2 methyl γ-aminobutyrate hydrochloride 
• 121-44-8 triethylamine 

Downstream Products

• 900174-38-1 methyl 2-(2-(isopropylthio)-5-nitrophenyl)pyrrolidine-3-carboxylate 

Relevant articles and documents

Design and synthesis of phenylpyrrolidine phenylglycinamides as highly potent and selective TF-FVIIa inhibitors

Inhibitors of the Tissue Factor/Factor VIIa (TF-FVIIa) complex are promising novel anticoagulants that show excellent efficacy and minimal bleeding in preclinical models. On the basis of a zwitterionic phenylglycine acylsulfonamide 1, a phenylglycine benz

BICYCLIC LACTAM FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS

The present invention provides novel bicyclic lactams derivatives, and analogues thereof, of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, B, C, W, Y, Z1, Z2, Z3, Z4, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.