90834-20-1

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 6-methyl-4-(2-phenylethenyl)-
• CAS NO: 90834-20-1
• Molecular Formula: C18H14O2
• Molecular Weight: 262.308
• Mol File: 90834-20-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 6-methyl-4-(2-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 6-methyl-4-(2-phenylethenyl)-(90834-20-1)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 6-methyl-4-(2-phenylethenyl)-(90834-20-1)

Safety Data

• Hazardous Substances Data: 90834-20-1(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 110-86-1 pyridine 
• 68747-27-3 (6-methyl-2-oxo-2H-chromen-4-yl)-acetic acid 
• 100-52-7 benzaldehyde 
• 1775-98-0 (E)-1-(2-hydroxy-5-methylphenyl)-3-phenylprop-2-en-1-one 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 613-84-3 2-hydroxy-5-methylbenzaldehyde 
• 6783-05-7 trans-2-phenylvinylboronic acid 

Downstream Products

• 114353-23-0 (+/-)-4-(2-hydroxy-5-methyl-phenyl)-6ξ-phenyl-cyclohex-4-ene-1r,2c,3ξ-tricarboxylic acid-1,2-anhydride-3-lactone 
• 122542-71-6 6-methyl-4-(β-m-tolylmercapto-phenethyl)-coumarin 
• 114001-70-6 6-methyl-4-(β-phenylsulfanyl-phenethyl)-coumarin 
• 122542-17-0 6-methyl-4-(β-p-tolylmercapto-phenethyl)-coumarin 

Relevant articles and documents

Rapid Access of Alkynyl and Alkenyl Coumarins via a Dipyridinium Methylide and Propargylamine Cascade Reaction

A DMAP-catalyzed cascade approach allowing facile assembly of alkynyl coumarins is reported. By virtue of reactive o-AQM (in situ generated from modular propargylamine) and a new synthetic equivalent of acyl carbene (from pyridinium ylide), the reaction proceeds smoothly to afford a variety of alkynyl coumarins in good-to-excellent yields. This transition-metal-free and oxidant-free process features moderate functional group tolerance, particularly the-Br group; thus, this protocol circumvents the inherent shortcomings of the existing Sonogashira coupling of coumarin triflates. This versatile method is also found to be applicable to the preparation of β-alkenyl coumarins, resembling the outcomes of the current Heck-type coupling reaction.