91892-48-7

Basic information

• Product Name: 1,2,4-Triazolo[4,3-a][1,3,5]triazine-5,7-diamine, N,N,N',N'-tetramethyl-3-(4-nitrophenyl)-
• CAS NO: 91892-48-7
• Molecular Formula: C14H16N8O2
• Molecular Weight: 328.333
• Mol File: 91892-48-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2,4-Triazolo[4,3-a][1,3,5]triazine-5,7-diamine, N,N,N',N'-tetramethyl-3-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Triazolo[4,3-a][1,3,5]triazine-5,7-diamine, N,N,N',N'-tetramethyl-3-(4-nitrophenyl)-(91892-48-7)
• EPA Substance Registry System: 1,2,4-Triazolo[4,3-a][1,3,5]triazine-5,7-diamine, N,N,N',N'-tetramethyl-3-(4-nitrophenyl)-(91892-48-7)

Safety Data

• Hazardous Substances Data: 91892-48-7(Hazardous Substances Data)

Upstream product

• 91892-39-6 2,4-bis(dimethylamino)-6-(4-nitrobenzylidenehydrazino)-1,3,5-triazine 
• 555-16-8 4-nitrobenzaldehdye 
• 10409-78-6 N²,N²,N⁴,N⁴-tetramethyl-2,4-diamino-6-hydrazinyl-[1,3,5]triazine 

Downstream Products

• 91892-57-8 5,7-bis(dimethylamino)-2-(4-nitrophenyl)<1,2,4>triazolo<1,5-a><1,3,5>triazine 

Relevant articles and documents

Triazines and Related Products. Part 26. Synthesis and Chemistry of Bicyclic Analogues of the Antitumour Drug 2,4,6-Tris(dimethylamino)-1,3,5-triazine (Hexamethylmelamine)

Interaction of 2,4-bis(dimethylamino)-6-hydrazino-1,3,5-triazine (1c) with aryl aldehydes yields a series of aryl hydrazones (4) which cyclise to 3-aryl-5,7-bis(dimethylamino)-1,2,4-triazolotriazines (6) with lead(VI) acetate in dichloromethane.Rearrangement of these bicycles in methanolic sodium hydroxide affords stable isomeric 2-aryl-5,7-bis(dimethylamino)triazolotriazines (7).Selected examples from both series of triazolotriazines were screened against the mouse M5076 reticulum cell sarcoma and P388 leukaemia in vivo but proved to have no antitumour activity.