92290-71-6

Basic information

• Product Name: 2-CHLORO-N-(3-PHENOXY-PHENYL)-ACETAMIDE
• Synonyms: 2-CHLORO-N-(3-PHENOXY-PHENYL)-ACETAMIDE
• CAS NO: 92290-71-6
• Molecular Formula: C₁₄H₁₂ClNO₂
• Molecular Weight: 261.7
• Mol File: 92290-71-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 438.9°Cat760mmHg
• Flash Point: 219.3°C
• Appearance: /
• Density: 1.279g/cm³
• Vapor Pressure: 6.65E-08mmHg at 25°C
• Refractive Index: 1.619
• CAS DataBase Reference: 2-CHLORO-N-(3-PHENOXY-PHENYL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-N-(3-PHENOXY-PHENYL)-ACETAMIDE(92290-71-6)
• EPA Substance Registry System: 2-CHLORO-N-(3-PHENOXY-PHENYL)-ACETAMIDE(92290-71-6)

Safety Data

• Hazardous Substances Data: 92290-71-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H12ClNO2/c15-10-14(17)16-11-5-4-8-13(9-11)18-12-6-2-1-3-7-12/h1-9H,10H2,(H,16,17)

Upstream product

• 79-04-9 chloroacetyl chloride 
• 3586-12-7 3-phenoxyaniline 

Downstream Products

• 1360180-34-2 2-azido-N-(3-phenoxyphenyl)acetamide 
• 1360180-48-8 N-((1-(2-oxo-2-(3-phenoxyphenylamino)ethyl)-1H-1,2,3-triazol-4-yl)methyl)-2-(3-oxobenzo[d]isothiazol-2(3H)-yl)acetamide 
• 1360180-66-0 N-(3-((1-(2-oxo-2-(3-phenoxyphenylamino)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-2-(3-oxobenzo[d]isothiazol-2(3H)-yl)acetamide 

Relevant articles and documents

Inhibition of dengue virus and west Nile virus proteases by click chemistry-derived benz[d]isothiazol-3(2H)-one derivatives

Two click chemistry-derived focused libraries based on the benz[d]isothiazol-3(2H)-one scaffold were synthesized and screened against Dengue virus and West Nile virus NS2B-NS3 proteases. Several compounds (4l, 7j-n) displayed noteworthy inhibitory activity toward Dengue virus NS2B-NS3 protease in the absence and presence of added detergent. These compounds could potentially serve as a launching pad for a hit-to-lead optimization campaign.