928321-84-0

Basic information

• Product Name: L-Serine, O-(1,1-dimethylethyl)-N-phenyl-, methyl ester
• CAS NO: 928321-84-0
• Molecular Formula: C14H21NO3
• Molecular Weight: 251.326
• Mol File: 928321-84-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: L-Serine, O-(1,1-dimethylethyl)-N-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Serine, O-(1,1-dimethylethyl)-N-phenyl-, methyl ester(928321-84-0)
• EPA Substance Registry System: L-Serine, O-(1,1-dimethylethyl)-N-phenyl-, methyl ester(928321-84-0)

Safety Data

• Hazardous Substances Data: 928321-84-0(Hazardous Substances Data)

Upstream product

• 17114-97-5 O-tert-butyl-L-serine methyl ester hydrochloride 
• 98-80-6 phenylboronic acid 
• 17083-26-0 O-tert-butyl-L-serine methyl ester 
• 17763-67-6 Phenyl triflate 

Relevant articles and documents

Formal synthesis of (+)-lactacystin from l-serine

A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-l-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.

NOVEL COMPOUNDS

This invention relates to novel amide derivatives and salts thereof. More particularly, it relates to novel amide derivatives and salts thereof which act as a ROCK inhibitor, to a pharmaceutical composition comprising the same and to a method of using the same therapeutically in the treatment and/or prevention of ROCK-related disease.