930-91-6

Basic information

• Product Name: 2-(HYDROXYMETHYL)CYCLOPENT-2-ENONE
• Synonyms: 2-(HYDROXYMETHYL)CYCLOPENT-2-ENONE
• CAS NO: 930-91-6
• Molecular Formula: C₆H₈O₂
• Molecular Weight: 112.13
• Mol File: 930-91-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 76 °C
• Boiling Point: 67-73 °C(Press: 0.1 Torr)
• Appearance: /
• Density: 1.344±0.06 g/cm3(Predicted)
• PKA: 5.38±0.20(Predicted)
• CAS DataBase Reference: 2-(HYDROXYMETHYL)CYCLOPENT-2-ENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(HYDROXYMETHYL)CYCLOPENT-2-ENONE(930-91-6)
• EPA Substance Registry System: 2-(HYDROXYMETHYL)CYCLOPENT-2-ENONE(930-91-6)

Safety Data

• Hazardous Substances Data: 930-91-6(Hazardous Substances Data)

Usage

Structure

Cyclic enone with a hydroxymethyl group attached to the cyclopentenone ring

Usage

Building block for various pharmaceuticals and agrochemicals in organic synthesis

Versatility

Can undergo oxidation, reduction, and addition reactions

Applications

Synthesis of complex organic molecules and used in fragrance and flavor compounds.

Upstream product

• 120-92-3 cyclopentanone 
• 109-94-4 formic acid ethyl ester 
• 936-52-7 1-(N-morpholino)cyclopent-1-ene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 62041-55-8 2-((dimethylamino)methylene)cyclopentanone 
• 1670-46-8 2-acetylcyclopentanaone 
• 15839-31-3 2-Ethoxy-cyclopenten-⁽¹⁾-carbaldehyd-⁽¹⁾-2.4-dinitro-phenylhydrazon 
• 15839-28-8 2-Methoxy-cyclopenten-⁽¹⁾-carbaldehyd-⁽¹⁾-2.4-dinitro-phenylhydrazon 
• 117890-55-8 2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 
• 88499-85-8 6,7-dihydro-5H-cyclopenta[b]pyridin-2-ol 
• 25536-14-5 methyl-2 cyclopentanopyridine 
• 133604-97-4 A-nor-9α,11α-oxido-9,10-secocholest-5(10)-en-6-yn-8β-yl benzoate 
• 133604-96-3 A-nor-9α,11α-oxido-9,10-secocholest-5(10)-en-6-yn-8β-ol 
• 107647-53-0 1-Benzyl-2-[1-trimethylsilanyloxy-meth-(E)-ylidene]-cyclopentanol 
• 107647-54-1 2-Benzyl-cyclopent-1-enecarbaldehyde 
• 441067-84-1 2-[(4-chloro-phenyl)-hydrazono]-cyclopentanone 
• 62136-38-3 (1E/Z)-cyclopentane-1,2-dione phenylhydrazome 
• 139192-68-0 (2S)-2-<(2R,4S)-4-phenyl-3-tosyl-1,3-oxazolidin-2-yl>cyclopentanone 

Relevant articles and documents

Improved Syntheses of 2-Hydroxymethylenecyclopentanone (2-Formylcyclopentanone) and Spirodec-6-en-1,8-dione

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Noteworthy mechanistic precedence in the exclusive formation of one regioisomer in the Beckmann rearrangement of ketoximes of 4-piperidones annulated to pyrazolo-indole nucleus by organocatalyst derived from TCT and DMF

Application of a very mild protocol to the Beckmann rearrangement of ketoximes of pyrazolo annulated oxocarbazole 5a and oxoazacarbazole 5b with the organocatalyst derived from 2,4,6-trichloro[1,3,5]triazine (TCT) and dimethylformamide (DMF) has been explored to provide a regioselective formation of the corresponding azepine 6a and 1,4-diazepine 6b respectively in good yield and purity. The mechanistic precedence for the exclusive formation of only one regioisomer has been discussed. Copyright Taylor & Francis Group, LLC.

[1,7]-Sigmatropic hydrogen shifts of A-norvitamin D analogues: Ring size and substituent effects on the provitamin D-vitamin D equilibrium

The [1,7]-sigmatropic hydrogen shift of the 11α-OH-A-norprevitamin D analogue 9 and its 11β-epimer 10 to the vitamin forms 24 and 25, respectively, was determined to be ～20 and ～10 times faster than that of provitamin D3 (1) to vitamin D3