931927-97-8

Basic information

• Product Name: 3-(4-trifluoromethylbenzyl)-1,3-dihydroindol-2-one
• Synonyms: 3-(4-trifluoromethylbenzyl)-1,3-dihydroindol-2-one
• CAS NO: 931927-97-8
• Molecular Formula: C₁₆H₁₂F₃NO
• Molecular Weight: 291
• Mol File: 931927-97-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-trifluoromethylbenzyl)-1,3-dihydroindol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-trifluoromethylbenzyl)-1,3-dihydroindol-2-one(931927-97-8)
• EPA Substance Registry System: 3-(4-trifluoromethylbenzyl)-1,3-dihydroindol-2-one(931927-97-8)

Safety Data

• Hazardous Substances Data: 931927-97-8(Hazardous Substances Data)

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 59-48-3 2-oxoindole 
• 349-95-1 4-(trifluoromethyl)benzylic alcohol 

Downstream Products

• 1351305-87-7 C₂₁H₂₀F₃NO₃ 
• 1351708-02-5 C₂₆H₃₀F₃N₃O₅ 

Relevant articles and documents

Synthesis, Characterization, and Reactivity of a Hypervalent-Iodine-Based Nitrooxylating Reagent

Herein, the synthesis and characterization of a hypervalent-iodine-based reagent that enables a direct and selective nitrooxylation of enolizable C?H bonds to access a broad array of organic nitrate esters is reported. This compound is bench stable, easy-

Chiral N,N′-Dioxide/Scandium(III)-Catalyzed Asymmetric Alkylation of N-Unprotected 3-Substituted Oxindoles

An efficient enantioselective alkylation of N-unprotected 3-substituted oxindoles was realized by using a chiral N,N′-dioxide/scandium(III) complex as the catalyst. A wide range of 3,3-dialkyl substituted oxindoles with quaternary stereocenters were obtained in high yields and ee values (up to 98% yield and 99% ee). (Figure presented.).

C-3 alkylation of oxindole with alcohols by Pt/CeO2 catalyst in additive-free conditions

In a series of transition metal-loaded CeO2 catalysts and Pt-loaded catalysts on various supports, Pt-loaded CeO2 shows the highest activity for the selective C-3 alkylation of oxindole with octanol. The catalyst is effective for alkylation of oxindole and N-substituted oxindole with a series of substituted benzyl, linear, hetero-aryl alcohols under additive-free conditions and is recyclable. Our results demonstrate the first additive-free catalytic system for this reaction. Mechanistic studies show that this system is driven by the borrowing-hydrogen pathway. Structure-activity relationship studies show that co-presence of surface Pt0 species on Pt metal clusters and basic support is indispensable for this catalytic system. This journal is the Partner Organisations 2014.