935-01-3

Basic information

• Product Name: Benzene, 1-buten-3-ynyl-, (E)-
• CAS NO: 935-01-3
• Molecular Formula: C10H8
• Molecular Weight: 128.174
• Mol File: 935-01-3.mol
• Article Data: 48

Chemical Properties

• CAS DataBase Reference: Benzene, 1-buten-3-ynyl-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-buten-3-ynyl-, (E)-(935-01-3)
• EPA Substance Registry System: Benzene, 1-buten-3-ynyl-, (E)-(935-01-3)

Safety Data

• Hazardous Substances Data: 935-01-3(Hazardous Substances Data)

Upstream product

• 17975-54-1 (Z)-3-methyl-4-((E)-3-phenylallylidene)isoxazol-5(4H)-one 
• 80814-98-8 (E)-diethyl (4-phenylbuta-1,3-dien-2-yl)phosphate 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 78980-65-1 cinnamoyl(ethoxycarbonyl)methylene(triphenyl)phosphorane 
• 1743-36-8 1-phenylbut-3-yn-1-ol 
• 1457-42-7 pyridazinyl-N-oxide 
• 108-86-1 bromobenzene 
• 80605-26-1 4-bromo-4-phenyl-1-butyne 
• 69142-92-3 4-chloro-4-phenyl-but-1-yne 
• 58335-31-2 1,3-dilithiopropyne 
• 100-52-7 benzaldehyde 
• 102-92-1 Cinnamoyl chloride 
• 140-10-3 (E)-3-phenylacrylic acid 
• 103-64-0 bromostyrene 

Downstream Products

• 935-01-3 (Z)-1-phenylbuten-3-yne 
• 1608-03-3 (E)-but-1-en-3-yn-1-ylbenzene 
• 124475-78-1 2-(2-Ethynyl-3-phenyl-aziridin-1-yl)-isoindole-1,3-dione 
• 1612145-39-7 (R,E)-2,6-diphenylhex-5-en-3-yn-2-ol 
• 1612145-71-7 (R,E)-[5-(allyloxy)hex-1-en-3-yne-1,5-diyl]dibenzene 
• 53081-57-5 (3Z,5E)-6-phenylhexa-3,5-dien-1-ol 
• 3864-19-5 (1E,3Z)-hexa-1,3,5-trien-1-ylbenzene 
• 21473-05-2 1-phenylcyclohexa-2,4-diene 
• 15619-32-6 1-phenyl-cyclohexa-1,3-diene 
• 134987-95-4 (2E,4E,6E)-7-phenyl-2,4-6-heptatrienoic acid piperidine 

Relevant articles and documents

Aminium cation-radical catalysed selective hydration of (E)-aryl enynes

The hydration of carbon-carbon triple bonds is an important and atom economic synthetic transformation. Herein, we report a mild and selective method for the catalytic Markovnikov hydration of (E)-aryl enynes to the corresponding enones, mediated through the bench-stable aminium salt, tris(4-bromophenyl)ammoniumyl hexachloroantimonate (TBPA). The chemoselective and diastereoselective method proceeds under neutral metal-free conditions, delivering excellent product yields from terminal and internal alkyne units. The synthesis of biologically important (E)-3-styrylisocoumarins, including a formal synthesis of the natural product achlisocoumarin III, demonstrates the utility of this novel transformation.

Iron-Catalyzed Tertiary Alkylation of Terminal Alkynes with 1,3-Diesters via a Functionalized Alkyl Radical

Direct oxidative C(sp)?H/C(sp3)?H cross-coupling offers an ideal and environmentally benign protocol for C(sp)?C(sp3) bond formations. As such, reactivity and site-selectivity with respect to C(sp3)?H bond cleavage have remained a persistent challenge. Herein is reported a simple method for iron-catalyzed/silver-mediated tertiary alkylation of terminal alkynes with readily available and versatile 1,3-dicarbonyl compounds. The reaction is suitable for an array of substrates and proceeds in a highly selective manner even employing alkanes containing other tertiary, benzylic, and C(sp3)?H bonds alpha to heteroatoms. Elaboration of the products enables the synthesis of a series of versatile building blocks. Control experiments implicate the in situ generation of a tertiary carbon-centered radical species.

Gold(I)-Catalyzed Oxidative 1,4-Additions of 3-En-1-ynamide with Nitrones via Carbon- versus Nitrogen-Addition Chemoselectivity

This work reports gold-catalyzed 1,4-oxofunctionalizations of 3-en-1-ynamides with nitrones, yielding two distinct E-configured products. We obtained 1,4-oxoarylation products from 3-en-1-ynamides bearing C(4)-electron-donating substituents and 1,4-oxoamination products from those analogues bearing C(4)-aryl substituents. We propose that if vinylgold carbenes are stable, imines undergo a para-arylation on these gold carbenes. If vinylgold carbenes are highly electron-deficient, this N-attack is irreversible to enable 1,4-oxoaminations.