941695-48-3

Basic information

• Product Name: N-(5-acetyl-pyridin-2-yl)-4-(3-hydroxy-propoxy)-benzenesulfonamide
• Synonyms: N-(5-acetyl-pyridin-2-yl)-4-(3-hydroxy-propoxy)-benzenesulfonamide
• CAS NO: 941695-48-3
• Molecular Weight: 350.395
• Mol File: 941695-48-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(5-acetyl-pyridin-2-yl)-4-(3-hydroxy-propoxy)-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-acetyl-pyridin-2-yl)-4-(3-hydroxy-propoxy)-benzenesulfonamide(941695-48-3)
• EPA Substance Registry System: N-(5-acetyl-pyridin-2-yl)-4-(3-hydroxy-propoxy)-benzenesulfonamide(941695-48-3)

Safety Data

• Hazardous Substances Data: 941695-48-3(Hazardous Substances Data)

Upstream product

• 940943-42-0 N-(5-acetyl-pyridin-2-yl)-4-iodo-benzenesulfonamide 
• 504-63-2 trimethyleneglycol 

Downstream Products

• 941695-50-7 N-(5-acetyl-pyridin-2-yl)-4-(3-bromo-propoxy)-benzenesulfonamide 

Relevant articles and documents

Identification of KD5170: A novel mercaptoketone-based histone deacetylase inhibitor

We report the identification of KD5170, a potent mercaptoketone-based Class I and II-histone deacetylase inhibitor that demonstrates broad spectrum cytotoxic activity against a range of human tumor-derived cell lines. KD5170 exhibits robust and sustained histone H3 hyperacetylation in HCT-116 xenograft tumors following single oral or iv dose and inhibition of tumor growth following chronic dosing.