94595-14-9 Usage
Molecular structure
2-(3,6-dioxo-5-phenylpiperazin-2-yl)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid has a complex molecular structure that includes a piperazine ring with phenyl and keto groups, as well as a thiazolidine ring with carboxylic acid functionality.
Piperazine ring
A heterocyclic compound consisting of six members with two nitrogen atoms and four carbon atoms. In this compound, the piperazine ring is substituted with a phenyl group and two oxygen atoms (keto groups).
Phenyl group
A phenyl group is a carbon-based functional group consisting of six carbon atoms connected in a ring, with each carbon atom bonded to a hydrogen atom. In this compound, the phenyl group is attached to the piperazine ring.
Keto groups
These are oxygen-containing functional groups with a carbonyl group (C=O) bonded to two carbon atoms. In this compound, two keto groups are present in the 3 and 6 positions of the piperazine ring.
Thiazolidine ring
A heterocyclic compound consisting of a four-membered ring with three carbon atoms and one sulfur atom. In this compound, the thiazolidine ring contains a carboxylic acid group.
Carboxylic acid functionality
A functional group consisting of a carbonyl group (C=O) bonded to a hydroxyl group (OH). In this compound, the carboxylic acid group is attached to the thiazolidine ring.
Pharmaceutical applications
The compound has potential pharmaceutical applications due to its structural features, which may interact with biological targets in the body.
Further research
More research is needed to fully understand the properties and potential uses of this compound, as its complex molecular structure may offer unique interactions with biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 94595-14-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,5,9 and 5 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 94595-14:
(7*9)+(6*4)+(5*5)+(4*9)+(3*5)+(2*1)+(1*4)=169
169 % 10 = 9
So 94595-14-9 is a valid CAS Registry Number.
94595-14-9Relevant articles and documents
Chemical reactivity of penicillins and cephalosporins. Intramolecular involvement of the acyl-amido side chain
Llinas, Antonio,Vilanova, Bartolome,Frau, Juan,Munoz, Francisco,Donoso, Josefa,Page, Michael I.
, p. 9052 - 9060 (2007/10/03)
The rate of degradation of 6-epi-ampicillin in acidic, neutral, and alkaline aqueous solutions was followed at 35 °C and an ionic strength of 0.5 mol dm-3 (KCl) by high-performance liquid chromatography (HPLC) and spectrophotometric assays. Pseudo-first-order rate constants were determined in a variety of buffer solutions, and the overall pH-rate profile was obtained by extrapolation to zero buffer concentration. The hydrolysis of 6- epi-ampicillin is subject to acid and hydroxide-ion catalysis and, for a penicillin, an unusual pH-independent reaction. Intramolecular general base- catalyzed hydrolysis by the side chain amido group is proposed to explain the enhanced rate of neutral hydrolysis of 6-epi-ampicillin and cephalosporins. The β-lactam of 6-epi-ampicillin also undergoes intramolecular aminolysis by nucleophilic attack of the 6-α side chain amino group to give a stable piperazine-2,5-dione derivative. The low effective molarity for intramolecular aminolysis of only 40 M is partly attributed to the unfavorable trans to cis isomerization about the 6-amide side chain required for ring closure. Theoretical calculations show that the intramolecular aminolysis of 6-epi-ampicillin nucleophilic attack occurs from the α-face of the β-lactam ring with an activation energy of 14.4 kcal/mol.
Liquid Chromatographic Determination of Penicillins by Postcolumn Degradation with Sodium Hypochlorite
Haginaka, Jun,Wakai, Junko
, p. 1896 - 1898 (2007/10/02)
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