950751-45-8

Basic information

• Product Name: (1aS,2aS)-ethyl 2-formyl 8,8a-dihydro-1aH-cyclopropa[c]pyrrolo[1,2-a]indole-1a-carboxylate
• Synonyms: (1aS,2aS)-ethyl 2-formyl 8,8a-dihydro-1aH-cyclopropa[c]pyrrolo[1,2-a]indole-1a-carboxylate
• CAS NO: 950751-45-8
• Molecular Weight: 269.3
• Mol File: 950751-45-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1aS,2aS)-ethyl 2-formyl 8,8a-dihydro-1aH-cyclopropa[c]pyrrolo[1,2-a]indole-1a-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1aS,2aS)-ethyl 2-formyl 8,8a-dihydro-1aH-cyclopropa[c]pyrrolo[1,2-a]indole-1a-carboxylate(950751-45-8)
• EPA Substance Registry System: (1aS,2aS)-ethyl 2-formyl 8,8a-dihydro-1aH-cyclopropa[c]pyrrolo[1,2-a]indole-1a-carboxylate(950751-45-8)

Safety Data

• Hazardous Substances Data: 950751-45-8(Hazardous Substances Data)

Upstream product

• 5059-30-3 2-chloroindole-3-carboxaldehyde 
• 145032-58-2 ethyl (1S,5R)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate 

Relevant articles and documents

One-step synthesis of heteroaromatic-fused pyrrolidines via cyclopropane ring-opening reaction: Application to the PKCβ inhibitor JTT-010

A ring-opening reaction of cyclopropanes with five-membered heteroaromatics having a leaving group at C(2) was found to provide heteroaromatic-fused pyrrolidines in one step. This reaction was successfully applied to the synthesis of the protein kinase C-β inhibitor JTT-010, which possesses a dihydropyrrolo[1,2-a]indole core.