95687-42-6

Basic information

• Product Name: (2S,4R)-benzyl 4-(tosyloxy)-2-((tosyloxy)methyl)pyrrolidine-1-carboxylate
• Synonyms: (2S,4R)-benzyl 4-(tosyloxy)-2-((tosyloxy)methyl)pyrrolidine-1-carboxylate
• CAS NO: 95687-42-6
• Molecular Weight: 559.661
• Mol File: 95687-42-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S,4R)-benzyl 4-(tosyloxy)-2-((tosyloxy)methyl)pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-benzyl 4-(tosyloxy)-2-((tosyloxy)methyl)pyrrolidine-1-carboxylate(95687-42-6)
• EPA Substance Registry System: (2S,4R)-benzyl 4-(tosyloxy)-2-((tosyloxy)methyl)pyrrolidine-1-carboxylate(95687-42-6)

Safety Data

• Hazardous Substances Data: 95687-42-6(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 1448706-36-2 (2R,4S)-2-hydroxymethyl-4-hydroxy-N-(carbobenzyloxy)pyrrolidine 
• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 95687-41-5 (2S,4R)-N1-(benzyloxycarbonyl)-4-hydroxy-2-(hydroxymethyl)-pyrrolidine 

Downstream Products

• 125043-95-0 2-benzyl-5-benzyloxycarbonyl-2,5-diazabicyclo[2.2.1]heptane 
• 95687-49-3 (2R,3S,4S)-3-Acetoxy-2-cyanomethyl-4-hydroxy-pyrrolidine-1-carboxylic acid benzyl ester 
• 95687-47-1 (2R,3S,4R)-3-Acetoxy-2-cyanomethyl-4-hydroxy-pyrrolidine-1-carboxylic acid benzyl ester 
• 95687-50-6 (2R,3S,4S)-3,4-Diacetoxy-2-cyanomethyl-pyrrolidine-1-carboxylic acid benzyl ester 
• 95687-46-0 (2R,3S,4R)-4-Acetoxy-2-cyanomethyl-3-hydroxy-pyrrolidine-1-carboxylic acid benzyl ester 
• 95687-45-9 (2R,3R,4R)-4-Acetoxy-2-cyanomethyl-3-iodo-pyrrolidine-1-carboxylic acid benzyl ester 
• 95687-44-8 (2R,4S)-2-Cyanomethyl-4-phenylselanyl-pyrrolidine-1-carboxylic acid benzyl ester 
• 95687-40-4 (R)-2-Cyanomethyl-2,5-dihydro-pyrrole-1-carboxylic acid benzyl ester 
• 95687-43-7 (2R,4R)-2-Cyanomethyl-4-(toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates

(R,R)-2,5-Diazabicyclo[ 2.2.1]heptanes are prepared from a compound of the formula STR1 wherein X and R2 are as defined herein, by heating with tosylchloride in pyridine, reacting the formed compound of the formula STR2 with a C1 -C6 alkylamine or ammonia, and reducing or hydrolyzing the formed compound of the formula STR3 wherein R1 is hydrogen or C1 -C6 alkyl.

AN ENANTIOSELECTIVE SYNTHESIS OF (+)-CROTANECINE

(2S,4R)-4-Hydroxyproline was elaborated into (+)-crotanecine via (1S,5R,8R)-8-hydroxy-2-oxa-6-azabicyclooctan-3-one