957777-99-0

Basic information

• Product Name: (4R,5S)-5-(4-methoxy-3-sulfamoylphenyl)-4-methyloxazolidin-2-one
• Synonyms: (4R,5S)-5-(4-methoxy-3-sulfamoylphenyl)-4-methyloxazolidin-2-one
• CAS NO: 957777-99-0
• Molecular Weight: 286.309
• Mol File: 957777-99-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,5S)-5-(4-methoxy-3-sulfamoylphenyl)-4-methyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-5-(4-methoxy-3-sulfamoylphenyl)-4-methyloxazolidin-2-one(957777-99-0)
• EPA Substance Registry System: (4R,5S)-5-(4-methoxy-3-sulfamoylphenyl)-4-methyloxazolidin-2-one(957777-99-0)

Safety Data

• Hazardous Substances Data: 957777-99-0(Hazardous Substances Data)

Upstream product

• 957777-98-9 (4R,5S)-5-(4-methoxyphenyl)-4-methyloxazolidin-2-one 

Downstream Products

• 112101-81-2 5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide 

Relevant articles and documents

Assymetric formal synthesis of (-)-formoterol and (-)-tamsulosin

Biologically important (2R)-2-amino-3-phenylpropanes consisted in commercial drugs including (R,R)-formoterol, and (R)-tamsulosin were prepared from chiral (2R)-aziridine-2-carboxylate without any chromatographic separation. Key reactions include regio- and stereoselective ring opening reaction of aziridin-2-yl-phenylmethanol and subsequent cyclization toward enantiopure 4,5-disubastitued oxazolidin-2-ones as synthetic intermediates.