966-46-1Relevant articles and documents
Zn-Mediated Hydrodeoxygenation of Tertiary Alkyl Oxalates
Ye, Yang,Ma, Guobin,Yao, Ken,Gong, Hegui
supporting information, p. 1625 - 1628 (2021/01/18)
Herein we describe a general, mild, and scalable method for hydrodeoxygenation of readily accessible tertiary alkyl oxalates by Zn/silane under Ni-catalyzed conditions. The reduction method is suitable for an array of structural motifs derived from tertiary alcohols that bear diverse functional groups, including the synthesis of a key intermediate en route to estrone.
An Enantioselective Version of the AB + D --> ABCD-Type Stereoid Total Synthesis
Quinkert, Gerhard,Grosso, Michael del,Bucher, Astrid,Bauch, Markus,Doering, Wolfgang,et al.
, p. 3617 - 3620 (2007/10/02)
Diene 1 and dienophile 4a in a Diels/Alder reaction mediated by a chiral ligand-modified Lewis acid enantioselectively furnish adduct 5a (chem. yield: 64percent; e.e: 73percent), which after partial deoxygenation and final enantioselection by recrystallization affords 5b.The latter compound can easily be converted via Torgov's pentaenone 6a into estrogens or progestogens. Key Words: stereoid total synthesis, enantioselective Lewis acid-mediated Diels/Alder reaction
Highly selective total synthesis of 19-nor-steroids via a photochemical key reaction: Racemic target compounds
Quinkert,Weber,Schwartz,et al.
, p. 2335 - 2371 (2007/10/02)
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