amisulpride basic information |
product name: | amisulpride |
synonyms: | 4-amino-n-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide;amisulpride;aminosultopride;dan-2163;deniban;socian;solian;4-amino-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzam |
cas: | 71675-85-9 |
mf: | c17h27n3o4s |
mw: | 369.48 |
einecs: | 275-831-7 |
product categories: | active pharmaceutical ingredients;antipsychotic;drug analogues;intermediates & fine chemicals;pharmaceuticals;dopamine receptor;deniban |
mol file: | 71675-85-9.mol |
amisulpride chemical properties |
mp | 124-128 |
storage temp. | 2-8°c |
solubility | dmso: ≥5 mg/ml |
form | solid |
color | white |
cas database reference | 71675-85-9(cas database reference) |
safety information |
hazard codes | xn |
risk statements | 22 |
safety statements | 22-24/25 |
wgk germany | 3 |
rtecs | cv2308701 |
msds information |
provider | language |
---|---|
amisulpride | english |
sigmaaldrich | english |
amisulpride usage and synthesis |
chemical properties | off-white solid |
usage | neuroleptic agent, an analogue of sulpiride. used as an antipsychotic. dopamine receptor antagonist |
usage | amisulpride is a neuroleptic agent, an analogue of sulpiride (s689145). amisulpride is used as an antipsychotic. amisulpride is a dopamine receptor antagonist. |
biological activity | potent, selective dopamine d 2 and d 3 receptor antagonist. k i values are 2.8 and 3.2 nm respectively for human d 2 and d 3 and > 1000 nm for human d 1 , d 4 and d 5 receptors. shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic d 2 /d 3 receptors at higher doses. preferentially interacts with limbic d 2 -like receptors in vivo . atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride. |
amisulpride basic information |
product name: | amisulpride |
synonyms: | 4-amino-n-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide;amisulpride;aminosultopride;dan-2163;deniban;socian;solian;4-amino-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzam |
cas: | 71675-85-9 |
mf: | c17h27n3o4s |
mw: | 369.48 |
einecs: | 275-831-7 |
product categories: | active pharmaceutical ingredients;antipsychotic;drug analogues;intermediates & fine chemicals;pharmaceuticals;dopamine receptor;deniban |
mol file: | 71675-85-9.mol |
amisulpride chemical properties |
mp | 124-128 |
storage temp. | 2-8°c |
solubility | dmso: ≥5 mg/ml |
form | solid |
color | white |
cas database reference | 71675-85-9(cas database reference) |
safety information |
hazard codes | xn |
risk statements | 22 |
safety statements | 22-24/25 |
wgk germany | 3 |
rtecs | cv2308701 |
msds information |
provider | language |
---|---|
amisulpride | english |
sigmaaldrich | english |
amisulpride usage and synthesis |
chemical properties | off-white solid |
usage | neuroleptic agent, an analogue of sulpiride. used as an antipsychotic. dopamine receptor antagonist |
usage | amisulpride is a neuroleptic agent, an analogue of sulpiride (s689145). amisulpride is used as an antipsychotic. amisulpride is a dopamine receptor antagonist. |
biological activity | potent, selective dopamine d 2 and d 3 receptor antagonist. k i values are 2.8 and 3.2 nm respectively for human d 2 and d 3 and > 1000 nm for human d 1 , d 4 and d 5 receptors. shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic d 2 /d 3 receptors at higher doses. preferentially interacts with limbic d 2 -like receptors in vivo . atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride. |