USD $10.00-100.00 / Kilogram
USD $10.00-100.00 / Kilogram
USD $10.00-100.00 / Kilogram
USD $1.00-10.00 / Kilogram
USD $10.00-100.00 / Kilogram
USD $1.00-10.00 / Kilogram
USD $8.20-8.80 / Kilogram
USD $8.20-8.80 / Kilogram
cas no.:74150-27-9
other names:pimobendan
mf:c19h18n4o2
place of origin: white crystalline powder
type:antibiotic and antimicrobial agents
grade standard:medicine grade
usage:animal pharmaceuticals
brand name:joye
purity:99%min
molecular weight:334.37
inchi:inchi=1/c19h18n4o2
refractive index:1.692
appearance:white crystalline powder
form:power
shelf life:24 months
assay:99.0~101.0%
grade:medical gelatin
heavy metals:≤10ppm
sulphated ash:≤0.1%
specification
itms |
standard |
results |
description |
white crystalline powder |
white crystalline powder |
ir indentification |
the infrared absorption spectrum is concordant with the reference spectrum of standard |
conform |
heavy metals |
≤10ppm |
<10ppm |
melting point |
about 242℃ |
244℃ |
solubility |
practically insoluble in water, freely soluble in dimethylformamide, slightly solulbe in acetone and in methanol |
conform |
sulphated ash |
≤0.1% |
0.05% |
solvent residue |
ethanol ≤2000ppm |
300ppm |
particle size |
98% pass through astm 40#screem |
100% |
related substances |
single impurity a: ≤0.1% single impurity b: ≤0.1% other impurity: ≤0.1% total impurities: ≤0.2% |
conform |
assay |
≥98.0% |
99.8% |
water |
≤1.0% |
<1.0% |
conclusion |
meet the requirements of ep6.0. . |
uses
pimobendan (cas no.74150-27-9) has strong positive inotropic effect and a strong vasodilator and platelet aggregation, and is used for the treatment of chronic and acute heart failure. it is used in the management of heart failure in dogs, most commonly caused by myxomatous mitral valve disease (also known as endocardiosis), or dilated cardiomyopathy.
kono chem co.,ltd is a leading producer of standardized herbal extracts, natural active ingredients and apis for pharmaceutical, health food and cosmetic industries.
the botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by pioneer. they include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.
with our phytopharmaceutical background and knowledge through experience, pioneer can also provide a wide range of analytical services and reference substances to our clients. in addition, we also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: sam-e tosylate disulfate; sam-e 1,4-butanedisulfonate; polycytidylic acid; polyinosinic acid; adenosine triphosphate disodium; and cytidine triphosphate disodium; these items are our strongest advantage in china. meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry.
recently, kono chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. as a gmp standardized manufacturer, our products can meet or even exceed the standards of cp2010, usp32, bp2005 and ep4. presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as usa, eu, south america and southeast asia. there are experienced technicians working for our institutes now, all of them are skilled. pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.