quick detail:
product name | diltiazem hydrochlorid |
other name | dilzem |
cas register number | 33286-22-5 |
einecs | 251-443-3 |
molecular formula | c22h27cln2o4s |
molecular weight | 450.98 |
molecular structure | |
appearance | white crystalline powder |
melting point | 212-214 °c |
assay | 99% |
coa:
test | analysis standard | results |
appearance | white to light yellow crystalline powder | white crystalline powder |
assay | ≥98.5%(calculated on the dried basic) | 99.5% |
clarity of solution | the solution is clear | complies |
optical rotation | +115-+120 | +116 |
identification | the light absorption exhibits a max uv236 | complies |
a blue colour is produced in the chloroform layre | complies | |
the infrared absorption sprctrum is consistent with tthe reference spectrum | complies | |
the aqueous solution yields the reaction characteristic of chlorides | complies | |
residual solvents, ppm |
toluene≤800 | 330 |
acetone≤5000 | 3000 | |
ethanol≤5000 | 3300 | |
isopropanol≤5000 | not detected | |
residue on ignition,% | ≤0.1 | 0.07 |
loss on drying ,% | ≤0.5 | 0.2 |
acidity ph | 4.3-4.6 | 4.4 |
heavy metal,ppm | ≤10 | complies |
sulfate,% | ≤0.024 | 0.021 |
arsenic,% | ≤0.0002 | complies |
related substances | the total impurities is not more than 0.5% | 0.41% |
conclusion | comply with cp2010 |