vitamin b6/ vitamin b6 powder /gmp approve vitamin b6 pyridoxine hydrochloride,cas:58-56-0
introduction:
vitamin b6 is a water-soluble vitamin and is part of the vitamin b complex group. several forms of the vitamin are known,
but pyridoxal phosphate (plp) is the active form and is a cofactor in many reactions of amino acid metabolism, including
transamination, deamination, and decarboxylation.plp also is necessary for the enzymatic reaction governing the release ofglucose from glycogen.
specification:
items |
specifications |
results |
appearance |
white fine powder/crystal |
complies |
identification |
infared absorption |
complies |
the retention time of the major peak in the chromatogram of the assay prepration corresponds to that in the chromatogram of the standard preparation, as obtained in the assay |
complies |
|
specific rotation |
between -28.6°and -35.0°, measured at 20° |
-32.8° |
water |
not more than 0.5% |
0.12% |
residue on ignition |
not more than 0.2% |
0.11% |
heavy metals |
not more than 0.001% |
complies |
related compounds by hplc(test1) |
fructose not more than 0.3% compound a not more than 0.3% other individual impurity not more than 0.1% total impurities not more than 0.5% |
fructose: 0.03% compound a: 0.04% total impurities: 0.07% |
particle size |
90% less than 350 microns |
complies |
limit of sulfamate and sulfate |
sulfamate ion not more than 0.10% sulfate ion not more than 0.10% |
complies |
residual solvent |
methylene chloride not more than 250μg/g |
not detected |
acetone not mor than 2500μg/g |
||
isopropanol not more than 5000μg/g |
||
ethanenitrile not more than 400μg/g |
||
n-hexane not more than 290μg/g |
||
ethyl acetate not more than 2500μg/g |
||
pyridine not more than 100μg/g |
||
assay |
topiramate contains not less than 98.0% and not more than the equivalent of 102.0% of c12h21no8s, calculated with reference to the anhydrous basis |
99.80% |
conclustion |
the material complies with respect to usp32 |
function:
1. the proper digestion and absorption of protein and fat;
2. to help in the essential amion acid tryptophan is converted to nicotinic acid;
3. to prevent all kinds of nerves, skin diseases;
4. alleviate vomiting;
5. promote the nucleic acid synthesis, to prevent the aging of tissues and organs;
6. lower the result of taking antidepressants caused by dry mouth and dysuria
7. slow night muscle spasms, cramps paralysis and other symptoms of hand,foot and neuritis;
8. is the natural the diuretic.
9. treatment of congenital hypofunction of metabolism;
10. prevent and treat vitamin b6 deficiency;
11. supplement to patients who need to consume more vitamin b6;
12. treatment of carpal tunnel syndrome.
application:
(1) treatment of congenital hypofunction of metabolism;
(2) prevent and treat vitamin b6 deficiency;
(3) supplement to patients who need to consume more vitamin b6;
(4) treatment of carpal tunnel syndrome.