USD $10.00-10.00 / Gram
USD $2.00-10.00 / Kilogram
USD $10.00-10.00 / Gram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
our company was built in 2009 with an iso certificate.
in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we had established stable business relationships with samsung,lg,merck,thermo fisher scientific and so on.
our main business covers the fields below:
1.noble metal catalysts (pt.pd...)
2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)
3.oled intermediates (fluorene,carbazole,boric acid...)
4.customs synthesis
our advantage:
1.higest quality and good package
2.fast delivery
3.better payment term
4.fast response to customer within 6 hours
5.good business credit in europe ,us ,japan ,korea
product name: imatinib mesylate
synonyms: 4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;sti-571;imatinib base(ima-3);imatinibmesylate/gleevec;imatinib methanesulfonate, sti-571, cgp-57148b, glivec,;imatinib mesylate (imatinib methanesulfonate);alpha-imatinib mesylate;imatinib mesylate(tinibs )
cas: 220127-57-1
mf: c30h35n7o4s
mw: 589.71
einecs:
product categories: active pharmaceutical ingredients;intermediates & fine chemicals;pharmaceuticals;tyrosine kinase inhibitors;aromatics;heterocycles;api;glivec, cgp-57148b, sti-571;antineoplastic;anti-cancer&immunity;inhibitors;anticancer
mol file: 220127-57-1.mol
imatinib mesylate structure
imatinib mesylate chemical properties
melting point 214-224°c
storage temp. -20°c freezer
solubility h2o: soluble10mg/ml, clear
color white to beige
cas database reference 220127-57-1(cas database reference)
safety information
hazard codes xn
risk statements 22
rtecs cv5520550
hazardous substances data 220127-57-1(hazardous substances data)
msds information
imatinib mesylate usage and synthesis
a small-molecule inhibitor imatinib mesylate (also called gleevec) is a small-molecule inhibitor of the fusion protein bcr-abl, the causal agent in chronic myelogenous leukemia.
as an inhibitor of pdgfr, imatinib mesylate appears to have utility in the treatment of a variety of dermatological diseases. imatinib has been reported to be an effective treatment for fip1l1-pdgfralpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.
chemical properties off-white solid
uses a tyrosine kinase inhibitor. highly specific for bcr-abl, the enzyme associated with chronic myelogenous leukemia (cml) and certain forms of acute lymphoblastic leukemia (all)
uses imatinib mesylate is orally bioavailability mesylate salt of imatinib, which is a multi-target inhibitor of v-abl, c-kit and pdgfr with ic50 of 0.6 μm, 0.1 μm and 0.1 μm, respectively. imatinib also known as gleevec, glivec, cgp-57148b, sti-571 & imatinib
uses imatinib mesylate (sti571) is an orally bioavailability mesylate salt of imatinib, which is a multi-target inhibitor of v-abl, c-kit and pdgfr with ic50 of 0.6 μm, 0.1 μm and 0.1 μm, respectively.