TIANFU CHEM Methyl cyanoacetate CAS NO.105-34-0

methyl cyanoacetate basic information
product name: methyl cyanoacetate
synonyms: aceticacid,cyano-,methylester;cyano-aceticacimethylester;malonic methyl ester nitrile;malonicacidmononitrilemethylester;methyl 2-cyanoacetate;methyl cyanoethanoate;methyl2-cyanoacetate;methylcyanoethanoate
cas: 105-34-0
mf: c4h5no2
mw: 99.09
einecs: 203-288-8
product categories: c2 to c5;carbonyl compounds;esters;organic chemical;piperazines
mol file: 105-34-0.mol
methyl cyanoacetate structure
methyl cyanoacetate chemical properties
melting point -13 °c
boiling point 204-207 °c(lit.)
density 1.123 g/ml at 25 °c(lit.)
vapor density 3.41 (vs air)
vapor pressure 0.2 mm hg ( 20 °c)
refractive index n20/d 1.417(lit.)
fp >230 °f
storage temp. store below +30°c.
solubility 54g/l
form liquid
color clear colorless to very slightly yellow
water solubility 54 g/l (20 ºc)
sensitive light sensitive
brn 773945
cas database reference 105-34-0(cas database reference)
nist chemistry reference acetic acid, cyano-, methyl ester(105-34-0)
epa substance registry system acetic acid, cyano-, methyl ester(105-34-0)

safety information
hazard codes xi
safety statements 24/25
ridadr 3276
wgk germany 1
rtecs ag4375000
hazard note irritant
tsca yes
hazardclass 6.1(b)
packinggroup iii
hs code 29269095

methyl cyanoacetate usage and synthesis
chemical properties clear colorless to very slighlty yellow liquid
uses pharmaceutical intermediate
methyl cyanoacetate preparation products and raw materials
raw materials ethyl cyanoacetate-->sodium cyanide-->methyl chloroacetate
preparation products 2-cyanoacetamide-->buspirone-->2,2-dibromo-2-cyanoacetamide-->methyl 2-amino-4-phenylthiophene-3-carboxylate-->2-amino-5-ethyl-thiophene-3-carboxylic acid methyl ester-->methyl 5-aminoisoxazole-4-carboxylate-->5-amino-3-methyl-thiophene-2,4-dicarboxylic acid dimethyl ester-->2-amino-5-phenyl-thiophene-3-carboxylic acid methyl ester-->solvent red 196-->cyanoacrylic acid methyl ester-->minoxidil-->2-amino-5,6-dihydro-4h-cyclopenta[b]thiophene-3-carboxylic acid methyl ester-->4-chloro-2,6-diaminopyrimidine-->2-amino-4-ethyl-5-methyl-thiophene-3-carboxylic acid methyl ester-->methyl 2-aminothiophene-3-carboxylate-->2,4-diamino-6-hydroxypyrimidine-->4-amino-6-chloropyrimidine-->basic yellow 40-->methyl 2-cyano-3-ethoxyacrylate -->methyl 2-cyano-2-propylpentanoate