USD $10.00-10.00 / Gram
USD $2.00-10.00 / Kilogram
USD $10.00-10.00 / Gram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
troglitazone basic information |
product name: | troglitazone |
synonyms: | resulin(tm);romglizone;troglitazone;2,4-thiazolidinedione,5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2h-1-b;5-(4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2;ci991;enzopyran-2-yl)methoxy)phenyl)methyl)-;gr92132x |
cas: | 97322-87-7 |
mf: | c24h27no5s |
mw: | 441.54 |
einecs: | |
product categories: | active pharmaceutical ingredients;intermediates & fine chemicals;pharmaceuticals;intracellular receptor;aromatics;heterocycles;sulfur & selenium compounds |
mol file: | 97322-87-7.mol |
troglitazone chemical properties |
melting point | 184-186°c |
storage temp. | store at -20°c |
solubility | dmso: 20 mg/ml |
form | solid |
color | white to yellow |
cas database reference | 97322-87-7(cas database reference) |
safety information |
safety statements | 22-24/25 |
wgk germany | 2 |
rtecs | xj5813130 |
troglitazone usage and synthesis |
chemical properties | crystalline solid |
usage | troglitazone is an an oral hypoglycemic agent which improves insulin sensitivity and decreases hepatic glucose production. antidiabetic. |
usage | antidiabetic;peroxisome proliferator-activated receptors activator |
biological activity | selective ppar γ receptor agonist (ec 50 values are 780 and 555 nm at murine and human ppar γ receptors respectively). displays no activity at ppar α or ppar δ receptors. antidiabetic agent; exerts potent glucose-lowering effects in insulin-resistant diabetic mice. displays anti-invasive effect on human breast cancer cells; reduces migration, adhesion and spreading on fibronectin-coated plates. also inhibits lamellipodia formation and actin polymerization. |
troglitazone preparation products and raw materials |
raw materials | p-hydroxybenzaldehyde-->trifluoromethanesulfonic anhydride-->2-methylpentane |
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