USD $10.00-10.00 / Gram
USD $10.00-10.00 / Gram
USD $10.00-10.00 / Gram
USD $8.20-8.80 / Kilogram
USD $10.00-10.00 / Gram
USD $1.00-10.00 / Kilogram
USD $9.00-99.00 / Kilogram
product name: | dofetilide |
synonyms: | tikosyn;tikosyn:uk-68798;beta-((p-methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide;methanesulfonamide, n-(4-(2-(methyl(2-(4-((methylsulfonyl)amino)phenoxy)ethyl)amino)ethyl) phenyl);tikosym;methyl[2-[4-(methylsulfonylamino)phenoxy]ethyl][4-(methylsulfonylamino)phenethyl]amine;n-[4-[2-[n-methyl-2-(4-methylsulfonylaminophenoxy)ethylamino]ethyl]phenyl]methanesulfonamide;u-68798 |
cas: | 115256-11-6 |
mf: | c19h27n3o5s2 |
mw: | 441.56 |
einecs: | |
product categories: | intermediates & fine chemicals;pharmaceuticals;sulfur & selenium compounds;pfizer compounds;inhibitors;active pharmaceutical ingredients;medicine intermediate;antiarrhythmic |
mol file: | 115256-11-6.mol |
dofetilide chemical properties |
melting point | 147-1490c |
storage temp. | store at rt |
solubility | dmso: >20mg/ml |
pka | 7.0, 9.0, 9.6(at 25℃) |
color | white to off-white |
cas database reference | 115256-11-6(cas database reference) |
safety information |
hazard codes | t,n |
risk statements | 61-48/22-51 |
safety statements | 53-22-36-57 |
msds information |
provider | language |
---|---|
dofetilide | english |
dofetilide usage and synthesis |
chemical properties | white crystalline solid |
uses | potassium channel blocker |
definition | chebi: a tertiary amino compound that is n-ethyl-n-methylethanamine substituted by a 4-[(methylsulfonyl)amino]phenoxy and a 4-[(methylsulfonyl)amino]phenyl group at the terminal carbon atoms respectively. it is used as an an i-arrhythmia drug. |
biological activity | selective potassium channel blocker. blocks herg k + channels; inhibits the rapid delayed-rectifier k + current (i kr ). displays class iii antiarrhythmic properties. |