1.Identification

1.1 GHS Product identifier

1.2 Other means of identification

1.3 Recommended use of the chemical and restrictions on use

1.4 Supplier's details

1.5 Emergency phone number

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 3

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity – single exposure, Category 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/… P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P312 Call a POISON CENTER/doctor/…if you feel unwell.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Refer for medical attention.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

In an antidotal study, phenobarbital, pentobarbital, and diphenylhydantoin were found to be effective in relieving the acute signs of intoxication in the rat. Intraperitoneal injection of phenobarbital (50 mg/kg) prevented tremor, diphenylhydantoin (100 mg/kg) by the same route reduced the toxic reaction, and pentobarbital (35 mg/kg intraperitoneally) removed the tremor reaction completely within 30 min. The combination of diphenylhydantoin with either of the barbiturates was effective in reducing the onset and severity of tremors whereas various other agents d-tubocurarine, atropine, meprobamate, diazepam, biperiden, and trimethadione) were ineffective ... .

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Liquid formulations containing organic solvents may be flammable. Water foam carbon dioxide powder

5.2 Specific hazards arising from the chemical

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2016)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

Personal protection: filter respirator for organic gases and vapors. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in an area without drain or sewer access. Keep in a well-ventilated room. Separated from strong oxidants, strong bases and food and feedstuffs.Store in an area without drain or sewer access. Keep in a well-ventilated room. Separated from strong oxidants, strong bases, food and feedstuffs

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

More stable in acidic solution than in alkaline solution.

10.3 Possibility of hazardous reactions

/Pyrethrins/ ... burn with difficulty. /Pyrethrins/A pyrethroid. This compound is an ester and nitrile. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Nitriles may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids).

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Incompatible with alkaline materials.

10.6 Hazardous decomposition products

When heated to decomposition it emits toxic fumes of /hydrogen chloride, nitrogen oxides and hydrogen cyanide/.

11.Toxicological information

Acute toxicity

• Oral: LD50 Rat oral 451 mg/kg
• Inhalation: LC50 Rat inhalation > 101 g/cu m/4 hr
• Dermal: LD50 Rat percutaneous > 5000 mg/kg

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

• Toxicity to fish: LC50 Pimephales promelas (fathead minnow) 0.42 mg/L/96 hr (confidence limit 0.39-0.46 mg/L), flow-through bioassay with measured concentrations, 24.5°C, dissolved oxygen 7.3 mg/L, hardness 44.8 mg/L calcium carbonate, alkalinity 40.9 mg/L calcium carbonate, and pH 7.8.
• Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water flea, age <24 hr); Conditions: freshwater, static, 20°C, pH 6.5; Concentration: 4.3 ug/L for 48 hr />95% purity
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: In a laboratory study using sediment and seawater collected from a salt marsh near Escambia County, FL, fenvalerate was observed to have a half-life of about 34 days(1); when the media was sterilized, fenvalerate showed no appreciable degradation after 28 days of incubation(1), thus suggesting that degradation was occurring through biotic means(SRC). In degradation tests using an activated sludge inoculum, the aerobic degradation rate of fenvalerate was 50-72% faster than in sterile controls(2); addition of a glucose medium to cometabolize the non-sterile flasks resulted in a 6-fold increase in the degradation rate(2). The aerobic (semi-open system, activated sludge inocula) biodegradation rate of fenvalerate was determined in tests using both inoculated and non-inoculated (control) experiments(3); the biodegradation half-life was determined to be 13 days(3). In seawater and seawater-sediment microcosm studies, the half-life of fenvalerate was determined to be 14-17 days in non-sterile systems and 33-41 days in sterile systems suggesting a presence of microbial activity(4). Through the application of an aquatic ecosystem model, fenvalerate added at concentrations of 5 and 25 ug/L, exhibited aquatic biodegradation half-lives of 3.5-4.3 days using moderately polluted river water (pH 7.7, dissolved oxygen 1.5 mg O2/L, 126 mg CaCo3/L; sand, carp, maintained at 15-19°C)(5).

12.3 Bioaccumulative potential

A BCF of 1,100 was measured for one isomer of fenvalerate (S,S-isomer) in carp in a 24 hr renewal exposure following 7 days of exposure(1). In a 28 day laboratory study, a steady-state BCF of 570 was measured in sheepshead minnow (Cyprinodon variegatus)(1). Log BCF values of 2.61 and 2.96, corresponding to BCFs of 407 and 912, respectively, in rainbow trout were reported(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high to very high(SRC), provided the compound is not metabolized by the organism(SRC). In a 28 day laboratory study, a steady-state BCF of 4,700 was measured in eastern oysters (Crassostrea virginica)(1). In a 30 day aquatic ecosystem study, fenvalerate BCFs of 100 for fish, 491 for snails and 412 for algae were measured(1); relatively low residues in the organisms were attributed to metabolism, especially by the fish(1). The presence of dissolved organic matter (concentration of 6.7 mg/L) may enhance bioconcentration in Oncorhynchus mykiss (rainbow trout) by up to a factor of 300(4).

12.4 Mobility in soil

The US Dept of Agriculture's Pesticide Properties Database reports a fenvalerate Koc of 5,300(1). Based upon measured isotherms and organic carbon content(2), the Koc values for fenvalerate in the silty-clay and clay sediments are log 4.04-4.22(2), corresponding to Koc values of 10,964 to 16,595(SRC). Freundlich sorption isotherms on corundum, quartz, kaolinite, and montmorillonite were 0.71, 0.6, 0.07, and 0.09, respectively(3). According to a classification scheme(4), this estimated Koc value suggests that fenvalerate is expected to be immobile in soil.

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

14.2 UN Proper Shipping Name

14.3 Transport hazard class(es)

14.4 Packing group, if applicable

14.5 Environmental hazards

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

16.Other information

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.