1000698-88-3

Basic information

• Product Name: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate
• Synonyms: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate;(2-Amino-4,5-difluoro-phenyl)-carbamic acid tert-butyl ester
• CAS NO: 1000698-88-3
• Molecular Formula: C₁₁H₁₄F₂N₂O₂
• Molecular Weight: 244.2378664
• Mol File: 1000698-88-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate(1000698-88-3)
• EPA Substance Registry System: tert-Butyl (2-amino-4,5-difluorophenyl)carbamate(1000698-88-3)

Safety Data

• Hazardous Substances Data: 1000698-88-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Tert-Butyl (2-amino-4,5-difluorophenyl)carbamate is used as a synthetic intermediate for the development of new drugs and treatments. Its unique structure allows for the creation of a wide range of pharmaceutical compounds with diverse therapeutic applications.
Used in Agrochemical Industry:
tert-Butyl (2-amino-4,5-difluorophenyl)carbamate is used as a fungicide, providing effective protection against fungal infections in crops. Its application helps to maintain crop health and yield, contributing to food security and agricultural productivity.
Used in Organic Synthesis:
Tert-Butyl (2-amino-4,5-difluorophenyl)carbamate is utilized as a versatile intermediate in organic synthesis, enabling the production of various chemical compounds with potential applications in medicine, agriculture, and materials science. Its unique structure and reactivity make it a valuable component in the synthesis of complex organic molecules.

Upstream product

• 1000698-90-7 tert-butyl 4,5-difluoro-2-nitrophenylcarbamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 76179-40-3 2-amino-4,5-difluoroaniline 
• 78056-39-0 4,5-difluoro-2-nitroaniline 

Downstream Products

• 1153859-80-3 2-[2-(3-Chloro-benzyl)-5,6-difluoro-benzoimidazol-1-yl]-2,N-dicyclohexyl-acetamide 
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• 1162676-15-4 4-{2-cyclohexyl-2-[5,6-difluoro-2-(4-trifluoromethyl-phenyl)-benzoimidazol-1-yl]-acetylamino}-benzoic acid ethyl ester 
• 1265885-62-8 N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide 
• 1265885-42-4 N-benzyl-2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-(4,4-difluoro-cyclohexyl)-acetamide 
• 1265885-28-6 N-benzyl-2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclopentyl-acetamide 
• 1265885-23-1 N-benzyl-2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclopropyl-acetamide 

Relevant articles and documents

NEW BENZIMIDAZOLE DERIVATIVES

The invention is concerned with novel benzimidazole derivatives of Formula (I) wherein A, n and R1 to R7 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds act on Farnesyl X receptor (FXR) and against cholesterol and lipid illnesses, diabetes, obesity, psoriasis, cancer, osteoporosis, Parkinson's and Alzheimer's disease.

NEW BENZIMIDAZOLE DERIVATIVES

The invention is concerned with novel benzimidazole derivatives of formula (I) wherein R1 to R6 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds can be used as medicaments.

SUBSTITUTED BENZIMIDAZOLE DERIVATIVES

The invention is concerned with novel substituted benzimidazole derivatives of formula (I) wherein R1 to R10 and X are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. T

METHYL-BENZIMIDAZOLE DERIVATIVES

The invention is concerned with novel substituted benzimidazole derivatives of formula (I) wherein R1 to R10 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds can be used as medicaments.

CARBOXYL- OR HYDROXYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES

This invention relates to novel carboxyl- or hydroxyl-substituted benzimidazole derivatives of formula (I) wherein R1 to R6 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.

BENZIMIDAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS FXR AGONISTS AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME

The invention is concerned with novel benzimidazole derivatives of formula (I) wherein R1 to R8 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind