- Compound, as well as preparation method and application thereof
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The application discloses a compound of which the structure is represented as the following formula, wherein R1 is selected from any one of F, Cl, Br, C1-C5 alkyl group, and a group having the structure as the formula (1), n = 0, 1, 2, 3, 4 or 5; the R2 is selected from any one of a group having the structure as the formula (1), a group having the structure as the formula (2), and a group having the structure as the formula (3). The compound has simple preparation method, can be used as a neuraminidase inhibitor, and has excellent antivirus activity.
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- A facile synthesis, antibacterial activity of pulvinone and its derivatives
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Pulvinone and several 3-fluoro-4-morpholino substituted pulvinone derivatives were synthesized in five steps from a common precursor, phenyl acetic acid. Most of synthetic morpholine substituted pulvinones showed inhibitory activity against Esherichia col
- Xu, Hai-Wei,Xu, Chao,Fan, Zi-Qi,Zhao, Ling-Jie,Liu, Hong-Min
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p. 737 - 739
(2013/02/25)
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- Synthesis of (E)- and (Z)-Pulvinones
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Two new routes to pulvinones have been developed, one of which involves a novel Wittig reaction.For the first time, members of the E-series, including the parent (E)-pulvinone, are reported and the structural elucidation of the geometric isomers is descri
- Campbell, Alexander C.,Maidment, Maurice S.,Pick, John H.,Stevenson, Donald F. M.
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p. 1567 - 1576
(2007/10/02)
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