1001412-59-4 Usage
Uses
Used in Organic Synthesis:
1H-Pyrrolo[2,3-b]pyridine-3-sulfonyl chloride is used as a versatile reagent for the introduction of the sulfonyl chloride functional group into organic molecules, facilitating a range of chemical reactions and the synthesis of complex organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1H-Pyrrolo[2,3-b]pyridine-3-sulfonyl chloride is employed as a building block for the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients, contributing to the development of new drugs with potential therapeutic applications.
Used as a Protecting Group in Organic Synthesis:
1H-Pyrrolo[2,3-b]pyridine-3-sulfonyl chloride is used as a protecting group for amines, which is crucial in organic synthesis to prevent unwanted reactions and ensure the selective formation of desired products.
Used in Drug Development:
Due to its reported antitumor and anti-inflammatory activities, 1H-Pyrrolo[2,3-b]pyridine-3-sulfonyl chloride is used in the development of new drugs, particularly for conditions that may benefit from these therapeutic properties.
Used in Pharmaceutical Research:
In pharmaceutical research, 1H-Pyrrolo[2,3-b]pyridine-3-sulfonyl chloride is utilized for exploring its potential as a lead compound in the discovery of novel therapeutic agents, given its demonstrated biological activities and chemical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1001412-59-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,1,4,1 and 2 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1001412-59:
(9*1)+(8*0)+(7*0)+(6*1)+(5*4)+(4*1)+(3*2)+(2*5)+(1*9)=64
64 % 10 = 4
So 1001412-59-4 is a valid CAS Registry Number.
1001412-59-4Relevant articles and documents
In situ anionic shielding for regioselective metalation: Directed peri and iterative metalation routes to polyfunctionalized 7-azaindoles
Schneider, Cedric,David, Emilie,Toutov, Anton A.,Snieckus, Victor
supporting information; experimental part, p. 2722 - 2726 (2012/04/17)
Strolling the ring: A general regioselective directed peri(C4)-metalation route to 1 through an in situ N-anionic protection of C2 is reported. The azaindoles may be elaborated by directed ortho metalation (DoM) and Suzuki coupling to more complex heterocyclic systems. An iterative ring-walk DoM sequence furnishes the exhaustively substituted 2. DMG=directed metalation group, TMEDA=N,N,N′,N′-tetramethylethylenediamine, TMS=trimethylsilyl. Copyright
Design and synthesis of human immunodeficiency virus entry inhibitors: Sulfonamide as an isostere for the α-ketoamide group
Lu, Rong-Jian,Tucker, John A.,Zinevitch, Tatiana,Kirichenko, Olga,Konoplev, Vitalii,Kuznetsova, Svetlana,Sviridov, Sergey,Pickens, Jason,Tandel, Sagun,Brahmachary, Enugurthi,Yang, Yang,Wang, Jian,Freel, Stephanie,Fisher, Shelly,Sullivan, Alana,Zhou, Jiying,Stanfield-Oakley, Sherry,Greenberg, Michael,Bolognesi, Dani,Bray, Brian,Koszalka, Barney,Jeffs, Peter,Khasanov, Alisher,Ma, You-An,Jeffries, Cynthia,Liu, Changhui,Proskurina, Tatiana,Zhu, Tong,Chucholowski, Alexander,Li, Rongshi,Sexton, Connie
, p. 6535 - 6544 (2008/09/16)
The crystal structures of many tertiary α-ketoamides reveal an orthogonal arrangement of the two carbonyl groups. Based on the hypothesis that the α-ketoamide HIV attachment inhibitor BMS 806 (formally BMS378806, 26) might bind to its gp120 target via a s
