1002334-13-5

Basic information

• Product Name: 1-Phenyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
• Synonyms: 1-Phenyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1-Phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl);1-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
• CAS NO: 1002334-13-5
• Molecular Formula: C₁₅H₁₉BN₂O₂
• Molecular Weight: 270.13456
• Mol File: 1002334-13-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 1-Phenyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole(1002334-13-5)
• EPA Substance Registry System: 1-Phenyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole(1002334-13-5)

Safety Data

• Hazardous Substances Data: 1002334-13-5(Hazardous Substances Data)

Usage

Uses

Used in Synthetic Chemistry:
1-Phenyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole is used as a reactive intermediate for various chemical reactions, particularly the Suzuki-Miyaura cross-coupling reaction. This reaction is extensively used in organic chemistry to form carbon-carbon bonds, making 1-Phenyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole a valuable asset in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Phenyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole is used as a building block for the development of new drugs. Its unique structure allows for the creation of novel compounds with potential therapeutic applications, contributing to the advancement of medicinal chemistry.
Used in Material Science:
1-Phenyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole is also used in material science for the synthesis of new materials with specific properties. Its versatility in forming carbon-carbon bonds enables the development of materials with tailored characteristics, such as improved stability or enhanced reactivity, for various applications.

Upstream product

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Relevant articles and documents

ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES

A compound having a structure of the formula Ir(LA)(LB), in which LA is a bidentate, tridentate, tetradentate, pentadentate, or hexadentate ligand and LB is a monodentate, bidentate, tridentate, or tetradentate ligand, or not present, and where the total denticity of LA plus LB is 6, and LA includes at least one structure of Formula I: is disclosed as a useful phosphorescent emitter compound.

Investigation of the scope and regiochemistry of alkynylboronate cycloadditions with sydnones

The cycloaddition of alkynylboronates and sydnones provides a convenientand highly regioselective method for the synthesis of a broad range of di-, tri-, and tetrasubstituted pyrazole boronic esters. The origins of an observed regiochemical divergence in the reactions of terminal alkyny lboronates with their more substituted analogues have been studied by DFT methods.

A sydnone cycloaddition route to pyrazole boronic esters

(Chemical Equation Presented) From dipole to diazole! A direct and regioselective route to functionalized pyrazole boronic esters is developed that employs the cycloaddition of alkynylboronates with sydnones. Functionalization of these products by Suzuki coupling and N-deprotection processes highlight the potential synthetic utility of these species.