100349-41-5

Basic information

• Product Name: diphenylmethyl (2S,5R,6S)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide
• Synonyms: 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-bromo-3,3-dimethyl-7-oxo-, diphenylmethyl ester, 4-oxide, (2S,5R,6S)-; Diphenylmethyl (2S,5R,6S)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide
• CAS NO: 100349-41-5
• Molecular Formula: C₂₁H₂₀BrNO₄S
• Molecular Weight: 462.3568
• Mol File: 100349-41-5.mol

Chemical Properties

• Boiling Point: 629.066°C at 760 mmHg
• Flash Point: 334.247°C
• Density: 1.582g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.688
• CAS DataBase Reference: diphenylmethyl (2S,5R,6S)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: diphenylmethyl (2S,5R,6S)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide(100349-41-5)
• EPA Substance Registry System: diphenylmethyl (2S,5R,6S)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide(100349-41-5)

Safety Data

• Hazardous Substances Data: 100349-41-5(Hazardous Substances Data)

Upstream product

• 5350-57-2 benzophenone hydrazone 
• 205320-26-9 6α-Bromopenicillanic acid 
• 551-16-6 6-aminopenicillanic acid 
• 37591-56-3 benzhydryl 6β-(phenylacetamido)penicillanate 1β-oxide 
• 551-16-6 6-Aminopenicillanic Acid 
• 100298-43-9 benzhydryl 6-diazopenicillanate 1β-oxide 

Downstream Products

• 162515-56-2 Benzhydryl (E)-(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(2-thiazol-2-yl-vinyl)-4-thia-1-aza-bicyclo [3.2.0]heptane-2-carboxylate 
• 162515-57-3 benzhydryl (Z)-(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(2-thiazol-2-yl-vinyl)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate 
• 162514-85-4 benzhydryl (E)-(2S,3S,5R)-3-(2-carbamoyl-vinyl)-3-methyl-4,4,7-trioxo-4-thia-1-aza-bicyclo [3.2.0]heptane-2-carboxylate 
• 162515-54-0 (2S,3S,5R)-3-Methyl-7-oxo-3-((E)-2-thiazol-2-yl-vinyl)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 162515-55-1 (2S,3S,5R)-3-Methyl-7-oxo-3-((Z)-2-thiazol-2-yl-vinyl)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 162515-03-9 (2S,3S,5R)-3-((E)-2-Chloro-vinyl)-3-methyl-4,4,7-trioxo-4λ⁶-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 162515-04-0 benzhydryl (Z)-(2S,3S,5R)-3-(2-chloro-vinyl)-3-methyl-4,4,7-trioxo-4-thia-1-aza-bicyclo [3.2.0]heptane-2-carboxylate 
• 162514-84-3 (2S,3S,5R)-3-((E)-2-Carbamoyl-vinyl)-3-methyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 162515-36-8 Benzhydryl (E)-(2S,3S,5R)-3-[3-(2-chloro-acetylamino-carbonyloxy)-propenyl]-3-methyl-4,4,7-trioxo-4-thia-1-aza-bicyclo [3.2.0]heptane-2-carboxylate 
• 180199-69-3 Benzhydryl (E)-(2S,3S,5R)-3-[2-(methoxy-methyl-carbamoyl)-vinyl]-3-methyl-4,4,7-trioxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate 
• 162515-35-7 benzhydryl (E)-(2S,3S,5R)-3-[3-(2-chloro-acetylaminocarbonyloxy)-propenyl]-3-methyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate 
• 162515-38-0 Benzhydryl (E)-(2S,3S,5R)-3-(carbamoyloxy-propenyl)-3-methyl-4,4,7-trioxo-4-thia-1-aza-bicyclo [3.2. 0]heptane-2-carboxylate 
• 162515-51-7 benzhydryl (E)-(2S,3S,5R)-3-methyl-3-[2-(1,2,4-oxadiazol-3-yl)-vinyl]-4,4,7-trioxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate 
• 180323-81-3 (E)-(2S,3S,5R)-3-methyl-7-oxo-3-{3-[(R)/(S)-(tetrahydropyran-2-yl)oxy]propenyl}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 

Relevant articles and documents

Design, synthesis, and evaluation of 2β-alkenyl penam sulfone acids as inhibitors of β-lactamases

A general method for synthesis of 2β-alkenyl penam sulfones has been developed. The new compounds inhibited most of the common types of β- lactamase. The level of activity depended very strongly on the nature of the substituent in the 2β-alkenyl group. Th