1003599-68-5Relevant articles and documents
Synthesis of antimalarial compounds fosmidomycin and FR900098 through N- or P-alkylation reactions
Suresh, Surisetti,Shyamraj, Dharavath,Larhed, Mats
, p. 1183 - 1188 (2013/03/14)
Two straightforward and convenient routes for the synthesis of the antimalarial agents FR900098 and fosmidomycin are described. In the key steps N- or P-alkylation reactions are used. The best overall yields of FR900098 and fosmidomycin in 15 mmol scale a
A novel short and efficient synthetic route to the antimalarial agent FR900098 and derivatives
Perruchon, Johann,Ortmann, Regina,Schlitzer, Martin
, p. 3553 - 3557 (2008/09/19)
We report here a new operationally simple, economical, and environmentally friendly multicomponent approach for a one-pot synthesis of the antimalarial agent FR900098. The reaction allows the fast construction of the compound from simple and commercially available substrates and reagents and is also applicable to the synthesis of modified derivatives of FR900098. Georg Thieme Verlag Stuttgart.