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Ethyl 4-chloro-2-methylquinoline-6-carboxylate is a chemical compound with a molecular formula C14H13ClNO2. It is an ester of 4-chloro-2-methylquinoline-6-carboxylic acid, characterized by its yellow color and solubility in organic solvents such as ethanol and dichloromethane. Ethyl 4-chloro-2-methylquinoline-6-carboxylate is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals.

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  • 100375-87-9 Structure
  • Basic information

    1. Product Name: ethyl 4-chloro-2-methylquinoline-6-carboxylate
    2. Synonyms: ethyl 4-chloro-2-methylquinoline-6-carboxylate
    3. CAS NO:100375-87-9
    4. Molecular Formula: C13H12ClNO2
    5. Molecular Weight: 249.69
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 100375-87-9.mol
  • Chemical Properties

    1. Melting Point: 113-114 °C
    2. Boiling Point: 355.4 °C at 760 mmHg
    3. Flash Point: 168.7 °C
    4. Appearance: /
    5. Density: 1.252 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. PKA: 3.49±0.50(Predicted)
    10. CAS DataBase Reference: ethyl 4-chloro-2-methylquinoline-6-carboxylate(CAS DataBase Reference)
    11. NIST Chemistry Reference: ethyl 4-chloro-2-methylquinoline-6-carboxylate(100375-87-9)
    12. EPA Substance Registry System: ethyl 4-chloro-2-methylquinoline-6-carboxylate(100375-87-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 100375-87-9(Hazardous Substances Data)

100375-87-9 Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 4-chloro-2-methylquinoline-6-carboxylate is used as an intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, Ethyl 4-chloro-2-methylquinoline-6-carboxylate is also utilized as an intermediate in the production of various agrochemicals. Its properties make it suitable for the synthesis of compounds that can be used in crop protection and other agricultural applications.
Safety Precautions:
It is important to handle Ethyl 4-chloro-2-methylquinoline-6-carboxylate with caution, as it may be harmful if ingested, inhaled, or comes into contact with the skin or eyes. Proper safety measures should be taken when handling and storing this chemical to minimize potential risks.

Check Digit Verification of cas no

The CAS Registry Mumber 100375-87-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,7 and 5 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 100375-87:
(8*1)+(7*0)+(6*0)+(5*3)+(4*7)+(3*5)+(2*8)+(1*7)=89
89 % 10 = 9
So 100375-87-9 is a valid CAS Registry Number.

100375-87-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 4-chloro-2-methylquinoline-6-carboxylate

1.2 Other means of identification

Product number -
Other names F2156-0005

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100375-87-9 SDS

100375-87-9Relevant articles and documents

Novel bisquinoline antimalarials. Synthesis, antimalarial activity, and inhibition of haem polymerisation

Raynes,Foley,Tilley,Deady

, p. 551 - 559 (2007/10/03)

We report the synthesis of two series of novel bisquinoline compounds that inhibit the growth of both chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum. To study the molecular basis of the action of these novel antimalarial

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