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2,3-Dihydro-4,5-dimethoxy-1H-indene-1-carbonitrile, a nitrogen-containing organic compound with the molecular formula C13H13NO2, is synthesized for various industrial applications. It is recognized for its moderate solubility in water and stability under normal conditions. 2,3-DIHYDRO-4,5-DIMETHOXY-1H-INDENE-1-CARBONITRILE has been a subject of interest in medicine and scientific research due to its potential biological and pharmacological properties. However, it is crucial to handle this chemical with care, as it can be hazardous if not properly managed.

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  • 100449-14-7 Structure
  • Basic information

    1. Product Name: 2,3-DIHYDRO-4,5-DIMETHOXY-1H-INDENE-1-CARBONITRILE
    2. Synonyms: 2,3-DIHYDRO-4,5-DIMETHOXY-1H-INDENE-1-CARBONITRILE
    3. CAS NO:100449-14-7
    4. Molecular Formula: C12H13NO2
    5. Molecular Weight: 203.24
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 100449-14-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,3-DIHYDRO-4,5-DIMETHOXY-1H-INDENE-1-CARBONITRILE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,3-DIHYDRO-4,5-DIMETHOXY-1H-INDENE-1-CARBONITRILE(100449-14-7)
    11. EPA Substance Registry System: 2,3-DIHYDRO-4,5-DIMETHOXY-1H-INDENE-1-CARBONITRILE(100449-14-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 100449-14-7(Hazardous Substances Data)

100449-14-7 Usage

Uses

Used in Pharmaceutical Industry:
2,3-Dihydro-4,5-dimethoxy-1H-indene-1-carbonitrile is used as an intermediate in the production of pharmaceuticals for its potential to contribute to the development of new drugs. Its unique chemical structure allows it to be a key component in the synthesis of various medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3-Dihydro-4,5-dimethoxy-1H-indene-1-carbonitrile is utilized as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its properties make it suitable for creating effective and targeted agricultural products.
Used in Organic Compounds Synthesis:
2,3-Dihydro-4,5-dimethoxy-1H-indene-1-carbonitrile is used as a building block in the synthesis of other organic compounds. Its versatility in chemical reactions enables the creation of a wide range of organic molecules for different applications across various industries.
Used in Scientific Research:
2,3-DIHYDRO-4,5-DIMETHOXY-1H-INDENE-1-CARBONITRILE is also used in scientific research as a subject of study for its potential biological and pharmacological properties. Researchers explore its interactions with biological systems and evaluate its efficacy and safety in various applications, contributing to the advancement of medicine and related fields.

Check Digit Verification of cas no

The CAS Registry Mumber 100449-14-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,4 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 100449-14:
(8*1)+(7*0)+(6*0)+(5*4)+(4*4)+(3*9)+(2*1)+(1*4)=77
77 % 10 = 7
So 100449-14-7 is a valid CAS Registry Number.

100449-14-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,5-dimethoxy-2,3-dihydro-1H-indene-1-carbonitrile

1.2 Other means of identification

Product number -
Other names 1H-Indene-1-carbonitrile,2,3-dihydro-4,5-dimethoxy

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100449-14-7 SDS

100449-14-7Relevant articles and documents

Conformationally Defined Adrenergic Agents. 2. Catechol Imidazoline Derivatives: Biological Effects at α1 and α2 Adrenergic Receptors

DeBernardis, John F.,Kyncl, John J.,Basha, Fatima Z.,Arendsen, David L.,Martin, Yvonne C.,et al.

, p. 463 - 467 (1986)

The synthesis and pharmacology of 2-(5,6-dihydroxy-1,2,3,4-tetrahydro-1-naphthyl)imidazoline (A-54741, 4), a very potent α-adrenergic agonist, are described.The change in biological activity resulting from variation of the carboxylic ring size of 4 from four through seven members (2-5) is presented, as well as an explanation that accounts for this change in activity by considering the "exactness of fit" of these compounds to both the α1- and α2-adrenergic receptors.Compound 4 was found in vitro to be a full agonist with greater potency at the α2 receptor (ED50 norepinephrine (NE)/ED50 4 = 188 +/- 22) than at the α1 receptor (ED50 NE/ED50 4 = 13 +/- 2).

Synthesis, conformation, and dopaminergic activity of 5,6-ethano-bridged derivatives of selective dopaminergic 3-benzazepines

Weinstock,Oh,DeBrosse,Eggleston,Wise,Flaim,Gessner,Sawyer,Kaiser

, p. 1303 - 1308 (2007/10/02)

To probe the suggestion that D-1 (DA1) dopamine receptors might possess an accessory π-binding site in a location complementary to a suitably oriented aromatic ring (i.e., in an axial orientation approximately orthogonal to the catechol nucleus

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