100464-19-5 Usage
Uses
Used in Organic Synthesis:
ETHYL-(2S,3S)-(P-NITROPHENYL)-OXIRANE-2,3-DICARBOXYLATE is used as a reagent in organic synthesis for the preparation of chiral α-substituted glycines and the synthesis of biologically active compounds. Its unique structure and functional groups enable it to participate in various reactions, contributing to the development of new and innovative chemical compounds.
Used in Pharmaceutical Development:
In the pharmaceutical industry, ETHYL-(2S,3S)-(P-NITROPHENYL)-OXIRANE-2,3-DICARBOXYLATE is used as a potential antitumor agent. Its chiral nature and functional groups make it a promising candidate for the development of new drugs targeting cancer cells. Researchers are investigating its potential applications in treating various types of cancer, leveraging its unique properties to enhance the effectiveness of cancer therapies.
Used in Chiral Chemistry:
ETHYL-(2S,3S)-(P-NITROPHENYL)-OXIRANE-2,3-DICARBOXYLATE is used as a chiral building block in the synthesis of enantiomerically pure compounds. Its 2S,3S configuration allows for the creation of chiral centers in target molecules, which is crucial for the development of drugs with specific biological activities. ETHYL-(2S,3S)-(P-NITROPHENYL)-OXIRANE-2,3-DICARBOXYLATE plays a vital role in the field of chiral chemistry, enabling the synthesis of enantiomerically pure compounds with desired properties.
Used in Research and Development:
In academic and industrial research settings, ETHYL-(2S,3S)-(P-NITROPHENYL)-OXIRANE-2,3-DICARBOXYLATE is used as a versatile chemical for exploring new reaction pathways and developing novel synthetic methods. Its unique structure and functional groups provide opportunities for researchers to investigate its reactivity and potential applications in various chemical transformations, contributing to the advancement of chemical science.
Check Digit Verification of cas no
The CAS Registry Mumber 100464-19-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,6 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 100464-19:
(8*1)+(7*0)+(6*0)+(5*4)+(4*6)+(3*4)+(2*1)+(1*9)=75
75 % 10 = 5
So 100464-19-5 is a valid CAS Registry Number.
100464-19-5Relevant articles and documents
Design, synthesis, and structure–activity relationship study of epoxysuccinyl–peptide derivatives as cathepsin B inhibitors
Zhang, Xiaoye,Yang, Xiaohong,Wang, Hongqiang,Li, Song,Guo, Kun,Jiang, Dan,Xiao, Junhai,Liang, Di
, p. 1240 - 1246 (2017/08/09)
Cathepsin B is a lysosomal cysteine protease involved in many diseases. The present research demonstrates that derivatives of epoxysuccinyl–peptide are effective and selective cathepsin B inhibitors. We synthesized a series of epoxysuccinyl–peptide deriva
COMPOSITIONS AND METHODS FOR SYNTHESIZING (2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYL-AMIDO-3-METHYLBUTANE ETHYL ESTER
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Paragraph 0057, (2017/07/06)
In alternative embodiments the invention provides methods for synthesizing AB-007 (also called loxistatin, E64d, EST or ((2S,3S)-trans-epoxysuccinyl-L-leucyl-amido-3-methylbutane ethyl ester) and its acid form E64c (loxistatin acid), and various synthetic
An improved preparation of the activity-based probe JPM-OEt and in situ applications
Chehade, Kareem A. H.,Baruch, Amos,Verhelst, Steven H. L.,Bogyo, Matthew
, p. 240 - 244 (2007/10/03)
A short, stereoselective synthesis of the general, cell permeable cathepsin probe JPM-OEt, is presented. The synthetic route is improved and described in more detail than previous reports for related compounds. This serves as a facile method for the synth
