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6-Chloro-2-Methyl-2H-pyridazin-3-one is an organic compound characterized by its unique molecular structure, which features a pyridazinone core with a chlorine atom at the 6th position and a methyl group at the 2nd position. 6-Chloro-2-Methyl-2H-pyridazin-3-one is known for its potential applications in the pharmaceutical industry due to its ability to interact with specific biological targets.

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  • 10071-38-2 Structure
  • Basic information

    1. Product Name: 6-Chloro-2-Methyl-2H-pyridazin-3-one
    2. Synonyms: 6-Chloro-2-Methyl-2H-pyridazin-3-one;6-chloro-2-methylpyridazin-3(2H)-one;3(2H)-Pyridazinone, 6-chloro-2-methyl-
    3. CAS NO:10071-38-2
    4. Molecular Formula: C5H5ClN2O
    5. Molecular Weight: 144.559
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 10071-38-2.mol
  • Chemical Properties

    1. Melting Point: 92-94 °C
    2. Boiling Point: 210.7±23.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.37±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. PKA: -1.47±0.70(Predicted)
    10. CAS DataBase Reference: 6-Chloro-2-Methyl-2H-pyridazin-3-one(CAS DataBase Reference)
    11. NIST Chemistry Reference: 6-Chloro-2-Methyl-2H-pyridazin-3-one(10071-38-2)
    12. EPA Substance Registry System: 6-Chloro-2-Methyl-2H-pyridazin-3-one(10071-38-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 10071-38-2(Hazardous Substances Data)

10071-38-2 Usage

Uses

Used in Pharmaceutical Industry:
6-Chloro-2-Methyl-2H-pyridazin-3-one is used as a key intermediate in the synthesis of histamine H3 receptor agonists for the treatment of sleeping disorders. These agonists help regulate the wakefulness and sleep-wake cycle, providing relief to individuals suffering from insomnia and other sleep-related issues.
In the preparation of histamine H3 receptor agonists, 6-Chloro-2-Methyl-2H-pyridazin-3-one plays a crucial role in modulating the histamine H3 receptor, which is involved in the regulation of histamine release and neurotransmission. By targeting this receptor, the compound can potentially improve sleep quality and duration, offering a promising therapeutic option for individuals with sleep disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 10071-38-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,0,7 and 1 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10071-38:
(7*1)+(6*0)+(5*0)+(4*7)+(3*1)+(2*3)+(1*8)=52
52 % 10 = 2
So 10071-38-2 is a valid CAS Registry Number.

10071-38-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-chloro-2-methylpyridazin-3-one

1.2 Other means of identification

Product number -
Other names 6-Chlor-2-methyl-2H-pyridazin-3-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10071-38-2 SDS

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