1007596-95-3

Basic information

• Product Name: (3R,4R)-4-aMino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: (3R,4R)-4-aMino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester;(3R,4R)-tert-Butyl 4-amino-3-hydroxypiperidine-1-carboxylate;tert-butyl (3R,4R)-4-amino-3-hydroxypiperidine-1-carboxylate;(3R,4R)-4-AMINO-1-BOC-3-HYDROXYPIPERIDINE
• CAS NO: 1007596-95-3
• Molecular Formula: C₁₀H₂₀N₂O₃
• Molecular Weight: 216.2774
• Mol File: 1007596-95-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: (3R,4R)-4-aMino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-4-aMino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester(1007596-95-3)
• EPA Substance Registry System: (3R,4R)-4-aMino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester(1007596-95-3)

Safety Data

• Hazardous Substances Data: 1007596-95-3(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
(3R,4R)-4-aMino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester is used as a chiral building block for the synthesis of biologically active compounds and pharmaceuticals. Its specific stereochemistry and functional groups enable the development of novel drugs with improved efficacy and selectivity.
Used in Drug Development:
(3R,4R)-4-aMino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester is used as a key intermediate in the synthesis of new drug candidates. Its unique structure and functional groups allow for the design and optimization of pharmaceuticals with enhanced potency, safety, and pharmacokinetic properties.
Used in Synthesis of Complex Organic Molecules:
(3R,4R)-4-aMino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester is used as a versatile synthetic building block for the preparation of complex organic molecules. Its functional groups and stereochemistry facilitate the construction of diverse molecular architectures with potential applications in various fields, such as materials science, agrochemistry, and specialty chemicals.

Upstream product

• 161157-50-2 tert-butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate 
• 66207-08-7 3,4-epoxy-piperidine-1-carboxylic acid benzyl ester 
• 167832-25-9 trans(±)benzyl-4-azido-3-hydroxypiperidine-1-carboxylate 
• 959617-87-9 benzyl (3R,4R)-4-amino-3-hydroxy-piperidine-1-carboxylate 
• 1161931-95-8 (3R,4R)-4-benzylamino-3-hydroxy-4-piperidine-1-carboxylic acid tert-butyl ester 
• 13139-12-3 tert-butyl 2,5-dioxopyrrolidin-1-yl carbonate 
• 1007596-94-2 (3R,4R)-4-aminopiperidin-3-ol 

Downstream Products

• 1007596-93-1 tert-butyl (3R,4R)-4-[(diphenylmethylene)amino]-3-hydroxypiperidine-1-carboxylate 
• 1007596-96-4 (3R,4R)-tert-butyl 3-azido-4-[(diphenylmethylene)amino]piperidine-1-carboxylate 
• 1161931-99-2 (3R,4R)-4-(4-bromo-2-nitro-phenylamino)-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

MINERALOCORTICOID RECEPTOR ANTAGONISTS AND METHODS OF USE

The present invention provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart failure, hypertension, diabetic nephropathy, or chronic kidney disease, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

PYRROLE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY

Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.

CHEMICAL COMPOUNDS

The use of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein X1, X2, X3, X4, Ra, p, R1,Z,Y, R2, R3 and R4 are as d