Synhesis of Heterocyclic Compounds. Part 46. The reactions of Malonamide and 2-Cyanoacetamide with Substituted Propenones
The synthesis of substituted 2-pyridone derivatives from malonamide (1) and 2-cyanoacetamide (2) is reported.Conjugate addition of these compounds to substituted propenones (3) and (4) leads to 6-hydroxy-2-piperidones, which can be dehydrated and aromatiz
Soto, Jose L.,Seoane, Carlos,Zamorano, Pilar,Rubio, Maria J.,Monforte, Alejandro,Quinteiro, Margarita
p. 1681 - 1686
(2007/10/02)
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