100798-34-3

Basic information

• Product Name: 2-PROPENOIC ACID, 3-[4-(2-METHOXY-2-OXOETHOXY)PHENYL]-, METHYL ESTER
• Synonyms: 2-PROPENOIC ACID, 3-[4-(2-METHOXY-2-OXOETHOXY)PHENYL]-, METHYL ESTER;3-[4-(2-METHOXY-2-OXOETHOXY)PHENYL]-2-PROPENOIC ACID METHYL ESTER
• CAS NO: 100798-34-3
• Molecular Formula: C₁₃H₁₄O₅
• Molecular Weight: 250.25
• Mol File: 100798-34-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-PROPENOIC ACID, 3-[4-(2-METHOXY-2-OXOETHOXY)PHENYL]-, METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PROPENOIC ACID, 3-[4-(2-METHOXY-2-OXOETHOXY)PHENYL]-, METHYL ESTER(100798-34-3)
• EPA Substance Registry System: 2-PROPENOIC ACID, 3-[4-(2-METHOXY-2-OXOETHOXY)PHENYL]-, METHYL ESTER(100798-34-3)

Safety Data

• Hazardous Substances Data: 100798-34-3(Hazardous Substances Data)

Upstream product

• 3943-97-3 methyl p-hydroxycinnamate 
• 96-34-4 methyl chloroacetate 
• 22042-71-3 (4-formylphenoxy)acetic acid 
• 3943-97-3 methyl 4-hydroxycinnamate 
• 96-32-2 bromoacetic acid methyl ester 
• 91345-17-4 4-carboxymethoxy-trans-cinnamic acid 

Downstream Products

• 100613-46-5 3-(4-methoxycarbonylmethoxy-phenyl)-propionic acid methyl ester 
• 198897-21-1 [4-(2-methoxycarbonylcyclopropyl)phenoxy]acetic acid 
• 156806-95-0 methyl 3-[4-(2-hydroxyethoxy)phenyl]acrylate 
• 386299-23-6 4-(2-acetoxyethoxy)cinnamyl acetate 
• 386299-30-5 (E)-3-[4-(2-Hydroxy-ethoxy)-phenyl]-propenol 
• 91345-17-4 4-carboxymethoxy-trans-cinnamic acid 
• 731845-75-3 (E)-2-(4-(3-methoxy-3-oxoprop-1-en-1-yl)phenoxy)acetic acid 
• 198897-20-0 methyl 2-[4-(methoxycarbonylmethoxy)phenyl]cyclopropanecarboxylate 
• 14234-87-8 3-[4-(carboxymethoxy)phenyl]propionic acid 

Relevant articles and documents

FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM

The present invention relates to compounds of formula I, which are functionalized phenolic compounds, and polymers formed from the same. Ar—[O—(X)p—R′]q??I Polymers formed from the functionalized phenolics are expected to have controllable degradation profiles, enabling them to release an active component over a desired time range. The polymers are also expected to be useful in a variety of medical applications.

Active site mapping of porcine liver esterase (PLE) and porcine pancreatic lipase (PPL): Stereo and regiochemical outcome of hydrolysis of conformationally constrained esters

The regio and stereoselectivity of PLE and PPL-catalyzed hydrolysis of a number of conformationally constrained substrates have been studied. The results are discussed based on the existing active site models for the two enzymes.

Novel Regioselective Ester Hydrolysis by Pig-Liver Esterase

Pig-liver esterase, which catalyzed the hydrolysis of substrates containing both saturated and αβ-unsaturated/cyclopropanecarboxylic esters (methyl and ethyl), was studied. An exclusive hydrolysis of the saturated esters was observed. Kinetic experiments revealed that the presence of deactivated carbonyl in the unsaturated/cyclopropanecarboxylic esters and their weaker bindings are both responsible for the observed specificity. The relative binding abilities of the substrates have been explained in light of Jones active-site model. The regioselectivity has been exploited in the synthesis of intermediates for the thromboxane synthetase inhibitor.