1009036-29-6 Usage
Uses
Used in Medicinal Chemistry and Pharmaceutical Research:
7-Fluoroquinazolin-4-amine is utilized as a key intermediate in the synthesis of diverse organic compounds, particularly in the development of new pharmaceutical agents. Its unique structure and reactivity make it a valuable component in the creation of novel therapeutics.
Used in Drug Candidate Development:
Due to its potential biological activity, 7-Fluoroquinazolin-4-amine is explored as a drug candidate for various therapeutic applications. Its specific interactions with biological targets could lead to the discovery of new treatments for a range of diseases.
Used in Agrochemical Development:
7-Fluoroquinazolin-4-amine may also find applications in the agrochemical industry, where it could be employed in the development of new pesticides or other agricultural chemicals, contributing to enhanced crop protection and yield.
Used in Specialty Chemicals Synthesis:
7-Fluoroquinazolin-4-amine's properties and reactivity make it a valuable intermediate in the synthesis of specialty chemicals for various industries, including but not limited to, the chemical, pharmaceutical, and materials science sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 1009036-29-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,9,0,3 and 6 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1009036-29:
(9*1)+(8*0)+(7*0)+(6*9)+(5*0)+(4*3)+(3*6)+(2*2)+(1*9)=106
106 % 10 = 6
So 1009036-29-6 is a valid CAS Registry Number.
1009036-29-6Relevant articles and documents
Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90
Huang, Kenneth H.,Barta, Thomas E.,Rice, John W.,Smith, Emilie D.,Ommen, Andy J.,Ma, Wei,Veal, James M.,Fadden, R. Patrick,Barabasz, Amy F.,Foley, Briana E.,Hughes, Philip F.,Hanson, Gunnar J.,Markworth, Christopher J.,Silinski, Melanie,Partridge, Jeffrey M.,Steed, Paul M.,Hall, Steven E.
scheme or table, p. 2550 - 2554 (2012/05/20)
A novel class of Hsp90 inhibitors, structurally distinct from previously reported scaffolds, was developed from rational design and optimization of a compound library screen hit. These aminoquinazoline derivatives, represented by compound 15 (SNX-6833) or 1-(2-amino-4-methylquinazolin-7-yl)-3,6,6-trimethyl-6, 7-dihydro-1H-indol-4(5H)-one, selectively bind to Hsp90 and inhibit its cellular activities at concentrations as low as single digit nanomolar.
Isoquinoline, Quinazoline and Phthalazine Derivatives
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Page/Page column 45, (2008/06/13)
Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein R0, R5, R6, R7, n, Q1-Q5, Y, and X1-X3 are as defined herein. Compounds of Formula I are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.
