463-52-5

Basic information

• Product Name: formamidine
• Synonyms: 2,2'-(1-oxoethane-1,2-diyl)dibenzoic acid;formimidamide
• CAS NO: 463-52-5
• Molecular Formula: CH₄N₂
• Molecular Weight: 44.0559
• Mol File: 463-52-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 81°C
• Boiling Point: 46.3 °C at 760 mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.07 g/cm³
• PKA: 11.60±0.40(Predicted)
• CAS DataBase Reference: formamidine(CAS DataBase Reference)
• NIST Chemistry Reference: formamidine(463-52-5)
• EPA Substance Registry System: formamidine(463-52-5)

Safety Data

• Hazardous Substances Data: 463-52-5(Hazardous Substances Data)

Usage

Definition

ChEBI: The smallest member of the class of carboxamidines being formic acid with the O and OH groups from the carboxy function replaced by NH and NH2 groups respectively. The parent of the class of formamidines.

Upstream product

• 44234-35-7 formimidic acid ethyl ester 
• 77287-34-4 formamide 
• 39895-55-1 4-(1,1-dimethylethyl)-benzenemethanamine 
• 104-84-7 para-methylbenzylamine 
• 90390-27-5 3,5-difluorobenzylamine 
• 6928-07-0 2-(1-naphthalenylmethylene)hydrazinecarboximidamide 
• 10269-01-9 3-bromobenzylamine 
• 34967-24-3 3,5-dimethoxybenzylamine 
• 100-46-9 benzylamine 
• 18469-52-8 methyl 4-(aminomethyl)benzoate 
• 3357-37-7 benzaldehyde diaminomethylenehydrazone 

Downstream Products

• 30368-49-1 desbutyl-desthiomethyl-terbutryn 
• 38109-77-2 3-amino-2-cyano-acrylic acid ethyl ester 
• 3752-24-7 4,5,6,7-tetrahydro-1H-benzimidazole 
• 33904-02-8 N-(3,4-dimethoxyphenyl)formamide 
• 1193-24-4 4,6-pyrimidinediol 
• 25286-58-2 1H-pyrimidine-4,6-dione 
• 34916-78-4 5,6-dimethyl-3H-pyrimidin-4-one 
• 73673-27-5 4,5-diethyl-1H-imidazole 
• 16357-69-0 4-amino-5-cyanopyrimidine 
• 21419-05-6 4-amino-5-phenylpyrimidine 
• 105258-24-0 5-Methoxy-2-[5-(2-phenyl-thiazol-4-yl)-pyrimidin-4-yl]-phenol 
• 100580-08-3 6-hydroxy-4-phenyl-1,4,5,6-tetrahydropyrimidine 
• 17759-27-2 4-methyl-6-phenylpyrimidine 
• 7552-07-0 1,3,4-thiadiazol-5-amine 

Relevant articles and documents

Iodine Catalyzed Oxidative Coupling of Diaminoazines and Amines for the Synthesis of 3,5-Disubstituted-1,2,4-Triazoles

A simple, convenient, transition metal-free one pot synthesis of 3,5-disubstituted-1,2,4-triazoles has been established. The innovation in this reaction is the use of easily available 1,1-diaminoazines as substrates. This method provides the products with wider substrate scope, at an expedited rate, and with relatively better yields in comparison to the reported methods. The reaction mechanism involves an initial intermolecular nucleophilic addition (facilitated by I2) followed by intramolecular nucleophilic cyclization.