1009303-77-8

Basic information

• Product Name: 2-METHOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-BENZENEMETHANOL
• Synonyms: 3-(Hydroxymethyl)-4-methoxyphenylboronic Acid Pinacol Ester;2-METHOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-BENZENEMETHANOL;(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol;BenzeneMethanol, 2-Methoxy-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
• CAS NO: 1009303-77-8
• Molecular Formula: C₁₄H₂₁BO₄
• Molecular Weight: 264
• EINECS: 200-589-5
• Mol File: 1009303-77-8.mol

Chemical Properties

• Boiling Point: 389.7±37.0 °C(Predicted)
• Appearance: /
• Density: 1.09±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 14.47±0.10(Predicted)
• CAS DataBase Reference: 2-METHOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-BENZENEMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-BENZENEMETHANOL(1009303-77-8)
• EPA Substance Registry System: 2-METHOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-BENZENEMETHANOL(1009303-77-8)

Safety Data

• Hazardous Substances Data: 1009303-77-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzenemethanol is used as a reagent for the introduction of the 1,3,2-dioxaborolane substructure into various organic molecules, enabling the formation of new compounds with enhanced properties and functionalities.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzenemethanol is used as a key building block in the synthesis of various drugs and drug candidates. Its unique structure allows for the development of new therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Synthesis:
2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzenemethanol is utilized as a starting material in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can lead to the development of more effective and environmentally friendly products.
Used in Materials Science:
In the field of materials science, 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzenemethanol is employed as a component in the development of functional materials with specific properties, such as conductivity, magnetism, or optical characteristics. Its integration into these materials can result in innovative applications in various industries, including electronics, energy, and nanotechnology.

Upstream product

• 80866-82-6 5-bromo-2-methoxy-benzyl alcohol 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1009298-09-2 AZD₈₀₅₅ 
• 938440-64-3 KU-63794 
• 1424432-38-1 C₂₅H₃₁N₅O₃S 
• 1009302-61-7 C₂₄H₂₉N₅O₄ 
• 1009302-80-0 C₂₅H₃₂N₆O₃ 
• 1009302-46-8 C₂₄H₃₁N₅O₄ 
• 1009302-47-9 C₂₃H₂₄N₆O₃ 
• 1421658-94-7 (S)-(5-(2-(tert-butyl)-4-(3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol 

Relevant articles and documents

MACROCYCLIC PYRIDAZINONE DERIVATIVES

The present invention relates to compounds of formula (I) Wherein R1, R2, R3, R4, L and Z have the meaning given in claim 1, and their use in the prophylaxis and treatment of diseases.

NOVEL HETEROCYCLIC DERIVATIVES

The invention relates to novel heterocyclic compounds of the formula (I) in which all of the variables are as defined in the specification, to their preparation, to their medical use, in particular to their use in the treatment of cancer and neurodegenrative disorders, and to medicaments comprising them.

MORPHOLINO PYRIMIDINE DERIVATIVES AND THEIR USE IN THERAPY

A compound of formula (I) or a salt, ester or prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, for example in the treatment of proliferative disease such as cancer and particularly in disease mediated by an mTOR kinase and/or one or more PI3K enzyme.