The present invention relates to compounds of formula (I) Wherein R1, R2, R3, R4, L and Z have the meaning given in claim 1, and their use in the prophylaxis and treatment of diseases.
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Page/Page column 62
(2014/08/20)
NOVEL HETEROCYCLIC DERIVATIVES
The invention relates to novel heterocyclic compounds of the formula (I) in which all of the variables are as defined in the specification, to their preparation, to their medical use, in particular to their use in the treatment of cancer and neurodegenrative disorders, and to medicaments comprising them.
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Page/Page column 56
(2012/08/27)
MORPHOLINO PYRIMIDINE DERIVATIVES AND THEIR USE IN THERAPY
A compound of formula (I) or a salt, ester or prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, for example in the treatment of proliferative disease such as cancer and particularly in disease mediated by an mTOR kinase and/or one or more PI3K enzyme.
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Page/Page column 131
(2008/06/13)
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